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  • Search Condition : Filter (MeSH = TOR Serine-Threonine Kinases / antagonists & inhibitors*)
Species Resource Title
Human and Animal Cells JHOM-1(RCB1676) , JHOM-2B(RCB1682) Dual inhibition of phosphatidylinositol 3'-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach for mucinous adenocarcinoma of the ovary.
Human and Animal Cells HuH-7(RCB1366) Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.
Human and Animal Cells HuH-7 mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.
Human and Animal Cells PANC-1(RCB2095) GDP Induces PANC-1 Human Pancreatic Cancer Cell Death Preferentially under Nutrient Starvation by Inhibiting PI3K/Akt/mTOR/Autophagy Signaling Pathway.
Human and Animal Cells HuCCT1(RCB1960) , SSP-25(RCB1293) , RBE(RCB1292) , YSCCC(RCB1549) , TGBC24TKB(RCB1196) , TFK-1(RCB2537) Synergistic antiproliferative effects of an mTOR inhibitor (rad001) plus gemcitabine on cholangiocarcinoma by decreasing choline kinase activity.
Human and Animal Cells KGN(RCB1154) Systematic drug sensitivity testing reveals synergistic growth inhibition by dasatinib or mTOR inhibitors with paclitaxel in ovarian granulosa cell tumor cells.
Human and Animal Cells Hep G2(RCB1648) Growth inhibition by NVP-BEZ235, a dual PI3K/mTOR inhibitor, in hepatocellular carcinoma cell lines.
Human and Animal Cells CACO-2(RCB0988) Augmented pentose phosphate pathway plays critical roles in colorectal carcinomas.
Human and Animal Cells JHOC-5(RCB1520) Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.
Human and Animal Cells JHOC-7(RCB1688) , JHOC-9(RCB2226) , HTOA(RCB0692) , JHOS-2(RCB1521) , JHOS-3(RCB1546) , JHOS-4(RCB1678) Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423.
Human and Animal Cells OCUB-F(RCB0882) mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer.
Human and Animal Cells TGBC1TKB(RCB1129) A potent therapeutics for gallbladder cancer by combinatorial inhibition of the MAPK and mTOR signaling networks.
Human and Animal Cells ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors.
Human and Animal Cells A549 Radio-sensitization effect of an mTOR inhibitor, temsirolimus, on lung adenocarcinoma A549 cells under normoxic and hypoxic conditions.
Human and Animal Cells A172(RCB2530) Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.
Human and Animal Cells PC-12(RCB0009) , SK-N-SH(RCB0426) Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD.