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論文 - 一覧

  • 16 Hits
  • 検索条件 : 絞込み (MeSH = TOR Serine-Threonine Kinases / antagonists & inhibitors*)
生物種 リソース名 タイトル
ヒト・動物細胞 JHOM-1(RCB1676) , JHOM-2B(RCB1682) Dual inhibition of phosphatidylinositol 3'-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach for mucinous adenocarcinoma of the ovary.
ヒト・動物細胞 HuH-7(RCB1366) Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.
ヒト・動物細胞 HuH-7 mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.
ヒト・動物細胞 PANC-1(RCB2095) GDP Induces PANC-1 Human Pancreatic Cancer Cell Death Preferentially under Nutrient Starvation by Inhibiting PI3K/Akt/mTOR/Autophagy Signaling Pathway.
ヒト・動物細胞 HuCCT1(RCB1960) , SSP-25(RCB1293) , RBE(RCB1292) , YSCCC(RCB1549) , TGBC24TKB(RCB1196) , TFK-1(RCB2537) Synergistic antiproliferative effects of an mTOR inhibitor (rad001) plus gemcitabine on cholangiocarcinoma by decreasing choline kinase activity.
ヒト・動物細胞 KGN(RCB1154) Systematic drug sensitivity testing reveals synergistic growth inhibition by dasatinib or mTOR inhibitors with paclitaxel in ovarian granulosa cell tumor cells.
ヒト・動物細胞 Hep G2(RCB1648) Growth inhibition by NVP-BEZ235, a dual PI3K/mTOR inhibitor, in hepatocellular carcinoma cell lines.
ヒト・動物細胞 CACO-2(RCB0988) Augmented pentose phosphate pathway plays critical roles in colorectal carcinomas.
ヒト・動物細胞 JHOC-5(RCB1520) Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.
ヒト・動物細胞 JHOC-7(RCB1688) , JHOC-9(RCB2226) , HTOA(RCB0692) , JHOS-2(RCB1521) , JHOS-3(RCB1546) , JHOS-4(RCB1678) Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423.
ヒト・動物細胞 OCUB-F(RCB0882) mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer.
ヒト・動物細胞 TGBC1TKB(RCB1129) A potent therapeutics for gallbladder cancer by combinatorial inhibition of the MAPK and mTOR signaling networks.
ヒト・動物細胞 ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors.
ヒト・動物細胞 A549 Radio-sensitization effect of an mTOR inhibitor, temsirolimus, on lung adenocarcinoma A549 cells under normoxic and hypoxic conditions.
ヒト・動物細胞 A172(RCB2530) Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.
ヒト・動物細胞 PC-12(RCB0009) , SK-N-SH(RCB0426) Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD.