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  • Search Condition : Filter (MeSH = TOR Serine-Threonine Kinases / metabolism*)
Species Resource Title
Mice RBRC02975 Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
Human and Animal Cells Hep G2 Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma.
Zebrafish UAS:GFP UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling.
Human and Animal Cells HS-Sch-2(RCB2230) , HS-PSS(RCB2362) , YST-1(RCB2136) Prognostic significance of AKT/mTOR and MAPK pathways and antitumor effect of mTOR inhibitor in NF1-related and sporadic malignant peripheral nerve sheath tumors.
Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) , Kato III(RCB2088) Antitumor effects of low-dose tipifarnib on the mTOR signaling pathway and reactive oxygen species production in HIF-1α-expressing gastric cancer cells.
Human and Animal Cells C2C12(RCB0987) Opening of Intermediate Conductance Ca2+-Activated K+ Channels in C2C12 Skeletal Muscle Cells Increases the Myotube Diameter via the Akt/Mammalian Target of Rapamycin Pathway.
Human and Animal Cells MCF7(RCB1904) Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
C.elegans tm3222 Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Human and Animal Cells MC3T3-G2/PA6(RCB1127) Gold nanoparticles enhance the differentiation of embryonic stem cells into dopaminergic neurons via mTOR/p70S6K pathway.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) , Atg7 +/+ MEFs(RCB3706) , Atg7 -/- MEFs(RCB3707) Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition.
Human and Animal Cells A172(RCB2530) Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.
Human and Animal Cells 293T(RCB2202) Inhibition of the glutamine transporter SNAT1 confers neuroprotection in mice by modulating the mTOR-autophagy system.
Human and Animal Cells MC3T3-E1(RCB1126) Intermittent pulsed electromagnetic field stimulation activates the mTOR pathway and stimulates the proliferation of osteoblast-like cells.
C.elegans tm1978 , tm4063 Insulin-like peptides and the mTOR-TFEB pathway protect Caenorhabditis elegans hermaphrodites from mating-induced death.
C.elegans tm5213 , tm5397 The mTOR Target S6 Kinase Arrests Development in Caenorhabditis elegans When the Heat-Shock Transcription Factor Is Impaired.
Human and Animal Cells TE-10(RCB2099) Uptake of collagen type I via macropinocytosis cause mTOR activation and anti-cancer drug resistance.
Drosophila Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification.
Algae NIES-3377 The checkpoint kinase TOR (target of rapamycin) regulates expression of a nuclear-encoded chloroplast RelA-SpoT homolog (RSH) and modulates chloroplast ribosomal RNA synthesis in a unicellular red alga.
C.elegans tm1340 Food-Dependent Plasticity in Caenorhabditis elegans Stress-Induced Sleep Is Mediated by TOR-FOXA and TGF-β Signaling.
Yeast FY7285 , pTN-L1(pAL-KS)? The RHEB-mTOR axis regulates expression of Tf2 transposons in fission yeast.