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  • Search Condition : Filter (MeSH = Thioredoxins / metabolism*)
Species Resource Title
Human and Animal Cells HCT116(RCB2979) Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells.
DNA material TMX2/pBiFC VN155 (RDB18581) , KPNB1-Cherry C pcDNA (RDB18582) , Impβ-VC155 pcDNA (RDB18583) , KPNB1/Flag pcDNA (RDB18584) , KPNB1/pQE80L (RDB18585) , Flag(C)-emerin/pcDNA (RDB18586) , Ran WT/Flag(N) pcDNA (RDB18587) , TMX2 WT/Flag pcDNA (RDB18588) , TMX2 isoform2/Flag pcDNA (RDB18589) , TMX2 WT/pcDNA (RDB18590) , ... Thioredoxin-related transmembrane protein 2 (TMX2) regulates the Ran protein gradient and importin-β-dependent nuclear cargo transport.
Human and Animal Cells Jurkat Diallyl trisulfide induces apoptosis in Jurkat cells by the modification of cysteine residues in thioredoxin.
Human and Animal Cells RAW 264(RCB0535) Rare sugar D-allose strongly induces thioredoxin-interacting protein and inhibits osteoclast differentiation in Raw264 cells.
Human and Animal Cells Thioredoxin and redox regulation of the nuclear receptor.
Human and Animal Cells RGM1(RCB0876) Geranylgeranylacetone promotes induction and secretion of thioredoxin in gastric mucosal cells and peripheral blood lymphocytes.
Human and Animal Cells Possible association of thioredoxin and p53 in breast cancer.
Human and Animal Cells COS-7(RCB0539) , CV-1(RCB0160) , HeLa(RCB0007) Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function.
C.elegans tm2720 , tm2820 TRX-1 Regulates SKN-1 Nuclear Localization Cell Non-autonomously in Caenorhabditis elegans.
DNA material , Human and Animal Cells CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). , 293T(RCB2202) A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition.
Prokaryotes E. coli Effect of signal peptide on stability and folding of Escherichia coli thioredoxin.
Prokaryotes E. coli Analysis of the organic hydroperoxide response of Chromobacterium violaceum reveals that OhrR is a cys-based redox sensor regulated by thioredoxin.
Drosophila Loss of Trx-2 enhances oxidative stress-dependent phenotypes in Drosophila.
Drosophila Thioredoxin suppresses Parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in Drosophila.
Yeast BYP1419 , BYP1805 A fluorescence resonance energy transfer (FRET)-based redox sensor reveals physiological role of thioredoxin in the yeast Saccharomyces cerevisiae.
C.elegans tm2047 , tm2720 The characterization of the Caenorhabditis elegans mitochondrial thioredoxin system uncovers an unexpected protective role of thioredoxin reductase 2 in β-amyloid peptide toxicity.
C.elegans tm2308 The thioredoxin TRX-1 modulates the function of the insulin-like neuropeptide DAF-28 during dauer formation in Caenorhabditis elegans.
Arabidopsis / Cultured plant cells, genes pda09920 The CHLI1 subunit of Arabidopsis thaliana magnesium chelatase is a target protein of the chloroplast thioredoxin.