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  • Search Condition : Filter (MeSH = Tumor Suppressor Protein p53 / metabolism*)
Species Resource Title
Mice RBRC05143 The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice.
DNA material CS-RfA-ETBsd (RDB07917) , CSII-CMV-MCS (RDB04377) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis.
Human and Animal Cells Saos-2(RCB0428) Development of p53 protein transduction therapy using membrane-permeable peptides and the application to oral cancer cells.
Human and Animal Cells TE-1(RCB1894) , TE-10(RCB2099) Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus.
Human and Animal Cells EoL-1 cell(RCB0641) p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells.
Human and Animal Cells 293(RCB1637) A DDX31/Mutant-p53/EGFR Axis Promotes Multistep Progression of Muscle-Invasive Bladder Cancer.
Human and Animal Cells HuH-7 Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis.
Human and Animal Cells HuH-7 Transcription factor KLF9 suppresses the growth of hepatocellular carcinoma cells in vivo and positively regulates p53 expression.
Drosophila DGRC#111109 VCP maintains nuclear size by regulating the DNA damage-associated MDC1-p53-autophagy axis in Drosophila.
Human and Animal Cells Kato III(RCB2088) , MKN74(RCB1002) , NUGC-4(RCB1939) , GSS(RCB2277) , GCIY(RCB0555) , MKN45(RCB1001) A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines.
Human and Animal Cells HeLa(RCB0007) , 293(RCB1637) Cytoplasmic localization of DGKζ exerts a protective effect against p53-mediated cytotoxicity.
Human and Animal Cells 293T(RCB2202) Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11.
Human and Animal Cells Hep G2 Inhibition of histone methyltransferase G9a attenuates liver cancer initiation by sensitizing DNA-damaged hepatocytes to p53-induced apoptosis.
Human and Animal Cells CW-2(RCB0778) Geranylgeranylacetone attenuates cisplatin-induced reductions in cell viability by suppressing the elevation of intracellular p53 content without heat shock protein induction.
Human and Animal Cells LM8(RCB1450) , 293(RCB1637) Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells.
Human and Animal Cells Lu99(RCB1900) Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation.
Human and Animal Cells MCF7(RCB1904) , 293T(RCB2202) SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.
Zebrafish Tg(isl1:GFP)rw0 Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2.
Human and Animal Cells 293T(RCB2202) Paclitaxel-induced aberrant mitosis and mitotic slippage efficiently lead to proliferative death irrespective of canonical apoptosis and p53.