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  • Search Condition : Filter (MeSH = Tumor Suppressor Protein p53 / metabolism*)
Species Resource
Human and Animal Cells Dynamic regulation of p53 subnuclear localization and senescence by MORC3.
Human and Animal Cells A549 E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53.
Zebrafish RIKEN WT (RW) , rw021 (Tg(ath5:GFP))? , rw255(piy)? Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53.
Mice C57BL-p53+/-(RBRC01361) Undifferentiated State Induced by Rb-p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CSII-CMV-MCS-IRES2-Bsd (RDB04385). Live-cell imaging visualizes frequent mitotic skipping during senescence-like growth arrest in mammary carcinoma cells exposed to ionizing radiation.
Human and Animal Cells Lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κB and inhibition of p53 activation.
Human and Animal Cells p53 accumulation is a strong predictor of recurrence in estrogen receptor-positive breast cancer patients treated with aromatase inhibitors.
Human and Animal Cells Novel 1p tumour suppressor Dnmt1-associated protein 1 regulates MYCN/ataxia telangiectasia mutated/p53 pathway.
Human and Animal Cells Lipopolysaccharide downregulates the expression of p53 through activation of MDM2 and enhances activation of nuclear factor-kappa B.
Human and Animal Cells MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism.
Human and Animal Cells Reversible induction of PARP1 degradation by p53-inducible cis-imidazoline compounds.
Human and Animal Cells Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells.
Human and Animal Cells Annexin A2 silencing induces G2 arrest of non-small cell lung cancer cells through p53-dependent and -independent mechanisms.
Human and Animal Cells A fluorescent-based high-throughput screening assay for small molecules that inhibit the interaction of MdmX with p53.
Human and Animal Cells DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
Human and Animal Cells Rhythmic control of the ARF-MDM2 pathway by ATF4 underlies circadian accumulation of p53 in malignant cells.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression.
Human and Animal Cells Effect of As2O3 on cell cycle progression and cyclins D1 and B1 expression in two glioblastoma cell lines differing in p53 status.
Mice A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.
Human and Animal Cells HeLa.S3 (RCB0191) CHO-K1 (RCB0285) Accumulation of p21 proteins at DNA damage sites independent of p53 and core NHEJ factors following irradiation.