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  • Search Condition : Filter (MeSH = Tumor Suppressor Proteins / genetics*)
Species Resource
Human and Animal Cells A549 , PC-14 Promoter methylation of DAL-1/4.1B predicts poor prognosis in non-small cell lung cancer.
Human and Animal Cells HeLa Transient strong reduction of PTEN expression by specific RNAi induces loss of adhesion of the cells.
INFORMATION Yeast A defect in protein farnesylation suppresses a loss of Schizosaccharomyces pombe tsc2+, a homolog of the human gene predisposing to tuberous sclerosis complex.
Human and Animal Cells SCCKN , SCCTF PTEN expression elicited by EGR-1 transcription factor in calyculin A-induced apoptotic cells.
Yeast The S. pombe genomic library A defect in protein farnesylation suppresses a loss of Schizosaccharomyces pombe tsc2+, a homolog of the human gene predisposing to tuberous sclerosis complex.
DNA material pTK5 (RDB01027) Cancer cell specific cytotoxic gene expression mediated by ARF tumor suppressor promoter constructs.
Mice TOP-GAL(RBRC02228) Bcl11b SWI/SNF-complex subunit modulates intestinal adenoma and regeneration after γ-irradiation through Wnt/β-catenin pathway.
Human and Animal Cells Frequent aberrant methylation of the promoter region of sterile alpha motif domain 14 in pulmonary adenocarcinoma.
Human and Animal Cells Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelioma.
Human and Animal Cells Methylation of the RASSF1A promoter is predictive of poor outcome among patients with Wilms tumor.
Human and Animal Cells Epigenetic silencing of HOPX promotes cancer progression in colorectal cancer.
Human and Animal Cells Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). Reduced level of the BCL11B protein is associated with adult T-cell leukemia/lymphoma.
Drosophila 5680R-1 Activation of JNK signaling links lgl mutations to disruption of the cell polarity and epithelial organization in Drosophila imaginal discs.
Drosophila FRT-lethal Frequent unanticipated alleles of lethal giant larvae in Drosophila second chromosome stocks.
Medaka HdrR-II1(IB176) , STII Molecular cloning and gene expression of the prox1a and prox1b genes in the medaka, Oryzias latipes.
DNA material Ax1 CA gfp (RDB01727) Lavendustin A enhances axon elongation in VHL gene-transfected neural stem cells.
Human and Animal Cells 293T(RCB2202) Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.
Human and Animal Cells NDRG2 is a candidate tumor-suppressor for oral squamous-cell carcinoma.
Human and Animal Cells Bmi1 regulates cell fate via tumor suppressor WWOX repression in small-cell lung cancer cells.