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  • Search Condition : Filter (MeSH = Ubiquitin-Protein Ligases / genetics*)
Species Resource Title
Human and Animal Cells 293T(RCB2202) SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.
Drosophila 11027R-2 , 11027R-3 , 30170R-1 , 30170R-2 , 4155R-1 , 4155R-2 , 9379R-2 , 9379R-3 , 9429R-1 , 9429R-2 , ... ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD.
Drosophila pBFvU6.2 , DGRC#104055 Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles.
Drosophila pBFv-U6.2 Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
C.elegans tm2026 BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining.
Human and Animal Cells HeLa , 293(RCB1637) Mitochondrial ubiquitin ligase activator of NF-κB regulates NF-κB signaling in cells subjected to ER stress.
Human and Animal Cells OS-RC-2(RCB0735) The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma.
Human and Animal Cells ZHBTc4(AES0136) The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes.
C.elegans tm1817 , tm2940 Nuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates.
Human and Animal Cells 201B7(HPS0063) Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease.
Human and Animal Cells UE7T-13(RCB2161) In Vivo MR Imaging of Dual MRI Reporter Genes and Deltex-1 Gene-modified Human Mesenchymal Stem Cells in the Treatment of Closed Penile Fracture.
C.elegans tm1361 The E3 Ubiquitin Ligase MIB-1 Is Necessary To Form the Nuclear Halo in Caenorhabditis elegans Sperm.
Human and Animal Cells 201B7(HPS0063) Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations.
Drosophila 17033R-3 Early girl is a novel component of the Fat signaling pathway.
C.elegans tm3543 RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans.
Human and Animal Cells TE-1(RCB1894) Targeted inhibition of the COP9 signalosome for treatment of cancer.
Human and Animal Cells 253G1(HPS0002) Tributyltin induces mitochondrial fission through Mfn1 degradation in human induced pluripotent stem cells.
Drosophila DGRC#115298 Angelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in Drosophila.
Mice RBRC02655 Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice.
C.elegans tm1779 , tm918 , tm598 The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans.