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  • Search Condition : Filter (MeSH = Ubiquitin-Protein Ligases / genetics*)
Species Resource
C.elegans tm598 , tm395 A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress.
C.elegans tm1380 , tm395 A mutation in CHN-1/CHIP suppresses muscle degeneration in Caenorhabditis elegans.
Drosophila P{GawB}ago[NP0850] (DGRC#103788) Notch-dependent expression of the archipelago ubiquitin ligase subunit in the Drosophila eye.
Mice MSM/Ms ES cell differentiation system recapitulates the establishment of imprinted gene expression in a cell-type-specific manner.
DNA material Ax1 CA gfp (RDB01727) Lavendustin A enhances axon elongation in VHL gene-transfected neural stem cells.
Yeast BYP1805 , BYP1804 A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation.
Zebrafish rw0 Neurogenic phenotype of mind bomb mutants leads to severe patterning defects in the zebrafish hindbrain.
Arabidopsis / Cultured plant cells, genes pda06233 Structure and biochemical function of a prototypical Arabidopsis U-box domain.
Drosophila 12298R-2 , 12298R-3 Systematic in vivo RNAi analysis identifies IAPs as NEDD8-E3 ligases.
Drosophila The RING-finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila.
Arabidopsis / Cultured plant cells, genes pda09625 The wavy growth 3 E3 ligase family controls the gravitropic response in Arabidopsis roots.
C.elegans RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2LRR-1 E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans.
C.elegans tm1779 , tm918 , tm598 The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans.
Mice B6;129-Xist<tm5Sado>(RBRC02655) Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice.
Mice DW/Pas-tbl Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase.
Cord blood stem cells for research 研究用ヒト臍帯血幹細胞 Human Herpesvirus-6 U14 Induces Cell-Cycle Arrest in G2/M Phase by Associating with a Cellular Protein, EDD.
Drosophila DGRC#115298 Angelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in Drosophila.
Drosophila 11154R-1 , 11154R-3 Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease.
Human and Animal Cells 201B7(HPS0063) Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations.
Human and Animal Cells TE-1(RCB1894) Targeted inhibition of the COP9 signalosome for treatment of cancer.