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  • 64 Hits
  • Search Condition : Filter (MeSH = Ubiquitin-Protein Ligases / metabolism*)
Species Resource
C.elegans tm1145 BRCA1-mediated ubiquitylation.
C.elegans tm808 The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated by the CUL-3MEL-26 E3 ligase in the C. elegans germ line.
Yeast cDNA library The transcription factor Atf1 binds and activates the APC/C ubiquitin ligase in fission yeast.
DNA material AxCANCre (RDB01748) Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.
DNA material pp53-Box RE-TK hRluc(F) (RDB05593) RNF43 interacts with NEDL1 and regulates p53-mediated transcription.
DNA material , Drosophila pUAST-Notch-flag (RDB08031) , DGRC#109169 , DGRC#109657 Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.
Arabidopsis / Cultured plant cells, genes pda06233 Structure and biochemical function of a prototypical Arabidopsis U-box domain.
Drosophila NP line Frizzled/PCP-dependent asymmetric neuralized expression determines R3/R4 fates in the Drosophila eye.
Yeast FY7507 , FY12697(L972 )? , FY10254(MY2354) , FY8437(MY566) , FY11440(MY3517) , FY11208(MY3285) , FY8476(MY624) , FY11159(MY3236) , FY11203(MY3280) Nuclear protein quality is regulated by the ubiquitin-proteasome system through the activity of Ubc4 and San1 in fission yeast.
Arabidopsis / Cultured plant cells, genes pda01364 A U-Box E3 ubiquitin ligase, PUB20, interacts with the Arabidopsis G-protein β subunit, AGB1.
DNA material pRSFlag_mmSumo1 (RDB06126) Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.
Arabidopsis / Cultured plant cells, genes rpc00008 Ubiquitin ligase ATL31 functions in leaf senescence in response to the balance between atmospheric CO2 and nitrogen availability in Arabidopsis.
Arabidopsis / Cultured plant cells, genes psx A plant U-box protein, PUB4, regulates asymmetric cell division and cell proliferation in the root meristem.
C.elegans The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.
DNA material pcDNA3-hRUNX1b (RDB15970) , pcDNA3-hRUNX1b-9KR (RDB15971) The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.
Zebrafish SAIGFF213A , UASGCaMP7a32A? , UASRFP1A ? RING finger protein 121 facilitates the degradation and membrane localization of voltage-gated sodium channels.
Cord blood stem cells for research The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.
Drosophila 3016R-2、5486R-3、4603R-2 The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.
C.elegans tm1380 , tm2692 The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover.
C.elegans tm1516 The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development.