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  • Search Condition : Filter (MeSH = Ubiquitin-Protein Ligases / metabolism*)
Species Resource
C.elegans tm5426 , tm1683 Two functionally distinct E2/E3 pairs coordinate sequential ubiquitination of a common substrate in Caenorhabditis elegans development.
Cord blood stem cells for research The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.
C.elegans tm2311 , tm3424 , tm2997 , tm3233 , tm3788 , tm4283 The UBR-1 ubiquitin ligase regulates glutamate metabolism to generate coordinated motor pattern in Caenorhabditis elegans.
DNA material pcDNA3-hRUNX1b (RDB15970) , pcDNA3-hRUNX1b-9KR (RDB15971) The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1.
C.elegans tm3968 The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.
Arabidopsis / Cultured plant cells, genes psx A plant U-box protein, PUB4, regulates asymmetric cell division and cell proliferation in the root meristem.
Human and Animal Cells MKN7(RCB0999) , MKN45(RCB1001) , MKN74(RCB1002) , Kato III(RCB2088) , NUGC-4(RCB1939) ASPP2 suppresses invasion and TGF-β1-induced epithelial-mesenchymal transition by inhibiting Smad7 degradation mediated by E3 ubiquitin ligase ITCH in gastric cancer.
C.elegans tm1380 UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins.
C.elegans tm2692 , tm3066 , tm3546 Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation.
C.elegans tm5426 Two functionally distinct E2/E3 pairs coordinate sequential ubiquitination of a common substrate in Caenorhabditis elegans development.
C.elegans tm1516 The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development.
C.elegans tm1380 , tm2692 The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover.
Drosophila CAS-0001 Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms.
DNA material CS-CA-MCS (RDB05963) ARIH2 Ubiquitinates NLRP3 and Negatively Regulates NLRP3 Inflammasome Activation in Macrophages.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons.
Tomato TOMJPF00001 Characterization of ubiquitin ligase SlATL31 and proteomic analysis of 14-3-3 targets in tomato fruit tissue (Solanum lycopersicum L.).
C.elegans tm2723 & tm2610 alleles A SUMO-Dependent Protein Network Regulates Chromosome Congression during Oocyte Meiosis.
Drosophila 4244R-1 Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover.
DNA material Genome Network Project Human cDNA IRAK004G03 (HGX001747). Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B.
Drosophila Godzilla-dependent transcytosis promotes Wingless signalling in Drosophila wing imaginal discs.