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論文 - 一覧

  • 101 Hits
  • 検索条件 : 絞込み (MeSH = Ubiquitin-Protein Ligases / metabolism*)
生物種 リソース名 タイトル
ヒト・動物細胞 HUDEP-2(RCB4557) The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells.
線虫 tm1046 , tm1515 O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1 modulate seizure susceptibility in C. elegans.
遺伝子材料 pMXs-IP-HA-Parkin (RDB19764) , pMXs-IP-GFP-Omp25 (RDB19786) Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.
遺伝子材料 pClgn1.1-Trim41-PA-1D4 (RDB19656) Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice.
ショウジョウバエ DGRC#125656 The tumor suppressor archipelago E3 ligase is required for spermatid differentiation in Drosophila testis.
ゼブラフィッシュ Tg(6xTcf/LefBS-miniP:d2EGFP) A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.
ショウジョウバエ 11861R-2 The E3 ubiquitin ligase adaptor Tango10 links the core circadian clock to neuropeptide and behavioral rhythms.
ヒト・動物細胞 OP9(RCB1124) Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence.
ヒト・動物細胞 C2C12(RCB0987) ZSWIM8 is a myogenic protein that partly prevents C2C12 differentiation.
ヒト・動物細胞 K562(RCB0027) Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
ヒト・動物細胞 HuH-7(RCB1366) Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma.
遺伝子材料 PINK1_WT-IRES-GFP-NLS (RDB18946) , PINK1_KD-IRES-GFP-NLS (RDB18947) , MUL1_WT-IRES-GFP-NLS (RDB18948) , MUL1_LD-IRES-GFP-NLS (RDB18949) Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1.
ゼブラフィッシュ hspGFF15A  , Tg(UAS:GFP) Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway.
ショウジョウバエ pBFv-U6.2 Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
遺伝子材料 pCAGGS (RDB08938) Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF.
線虫 tm1145 BRCA1-BARD1 Regulates Axon Regeneration in Concert with the Gqα-DAG Signaling Network.
線虫 Meiotic Double-Strand Break Processing and Crossover Patterning Are Regulated in a Sex-Specific Manner by BRCA1-BARD1 in Caenorhabditis elegans.
ヒト・動物細胞 293T(RCB2202) Degradation of host ubiquitin E3 ligase Itch by human cytomegalovirus UL42.
ヒト・動物細胞 Hepa 1-6(RCB1638) Sp1 is a substrate of Keap1 and regulates the activity of CRL4AWDR23 ubiquitin ligase toward Nrf2.
ショウジョウバエ Antagonistic control of myofiber size and muscle protein quality control by the ubiquitin ligase UBR4 during aging.