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  • 検索条件 : 絞込み (MeSH = Wnt Signaling Pathway / drug effects*)
生物種 リソース名 タイトル
ヒト・動物細胞 BM‐MSCs Human bronchial epithelial cell-derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF-β-WNT crosstalk.
ゼブラフィッシュ Tg(Tcf/Lef-miniP:dGFP) Protocol for rapid assessment of the efficacy of novel Wnt inhibitors using zebrafish models.
ヒト・動物細胞 HeLa(RCB0007) A pyridinium‑type fullerene derivative suppresses primary effusion lymphoma cell viability via the downregulation of the Wnt signaling pathway through the destabilization of β‑catenin.
ヒト・動物細胞 293T(RCB2202) 9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β without Depending on Casein Kinase 1α.
ヒト・動物細胞 HCT116(RCB2979) Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway.
ゼブラフィッシュ RIKEN WT Clotrimazole inhibits the Wnt/β-catenin pathway by activating two eIF2α kinases: The heme-regulated translational inhibitor and the double-stranded RNA-induced protein kinase.
ゼブラフィッシュ RIKEN WT IMU1003, an atrarate derivative, inhibits Wnt/β-catenin signaling.
ヒト・動物細胞 ECC10(RCB0983) E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling.
ヒト・動物細胞 ATDC5(RCB0565) Verapamil protects against cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling.
ヒト・動物細胞 ATDC5(RCB0565) Xanthan Gum Ameliorates Osteoarthritis and Mitigates Cartilage Degradation via Regulation of the Wnt3a/β-Catenin Signaling Pathway.
ショウジョウバエ The glycosphingolipid MacCer promotes synaptic bouton formation in Drosophila by interacting with Wnt.
ヒト・動物細胞 B16/BL6(RCB2638) Anti-tumor effects of differentiation-inducing factor-1 in malignant melanoma: GSK-3-mediated inhibition of cell proliferation and GSK-3-independent suppression of cell migration and invasion.
ヒト・動物細胞 Hep G2(RCB1886) , ATDC5(RCB0565) Molecular hydrogen suppresses activated Wnt/β-catenin signaling.
ゼブラフィッシュ Tg(6xTcf/LefBS-miniP:d2EGFP) Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer.
遺伝子材料 pTcf7wtluc (RDB02968) , pTcf7mtluc (RDB02969). APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.
ヒト・動物細胞 ST2(RCB0224) Activation of the Wnt pathway through AR79, a GSK3β inhibitor, promotes prostate cancer growth in soft tissue and bone.
ヒト・動物細胞 ST2(RCB0224) Lignin Induces ES Cells to Differentiate into Neuroectodermal Cells through Mediation of the Wnt Signaling Pathway.
ヒト・動物細胞 HuH-7 Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib.
ゼブラフィッシュ Tg(6xTcf/LefBS-miniP:d2EGFP) Identification and characterization of a novel small-molecule inhibitor of β-catenin signaling.
実験動物マウス RBRC04609 WNT5a is required for normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signaling.