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Species Resource Title
DNA material pCMV-myc-shootin1a (S101D, S249D) (RDB19947) , pCMV-myc-shootin1a (S101A, S249A) (RDB19948) , pCMV-myc-RNAi refractory shootin1a (S101D, S249D) (RDB19951) , pCMV-myc-RNAi refractory shootin1a (S101A, S249A) (RDB19952) Conversion of a signal into forces for axon outgrowth through Pak1-mediated shootin1 phosphorylation.
Human and Animal Cells T3M-1 Clone2(RCB1015) , T3M-1 Cl-10(RCB1017) , CJM(RCB1034) Potential role of p21 Activated Kinase 1 (PAK1) in the invasion and motility of oral cancer cells.
Human and Animal Cells 293T(RCB2202) INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.
C.elegans tm403 , tm1962 Redundant canonical and noncanonical Caenorhabditis elegans p21-activated kinase signaling governs distal tip cell migrations.
C.elegans tm403 p21-activated kinase interacts with Wnt signaling to regulate tissue polarity and gene expression.
C.elegans tm3334 , tm1340 , tm2299 , tm812 Multiple cytoskeletal pathways and PI3K signaling mediate CDC-42-induced neuronal protrusion in C. elegans.
Human and Animal Cells DT40(RCB1464) , Vav3^(-) DT40(Vav3^(-) DT40) , PLC-γ2^(-) DT40(RCB1469) Rac1/p21-activated kinase pathway controls retinoblastoma protein phosphorylation and E2F transcription factor activation in B lymphocytes.
Drosophila 14895R-1 , 2248R-2 , 9774R-2 , 18255R-3 Requirement for Pak3 in Rac1-induced organization of actin and myosin during Drosophila larval wound healing.
C.elegans tm403 Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles.
C.elegans tm1962 A RAC/CDC-42-independent GIT/PIX/PAK signaling pathway mediates cell migration in C. elegans.