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  • Search Condition : Filter (MeSH = rab GTP-Binding Proteins / metabolism*)
Species Resource Title
DNA material pEGFP-C1-FOP(FGFR1OP) (RDB20236) RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly.
C.elegans tm4085 , tm2526 rab-27 acts in an intestinal pathway to inhibit axon regeneration in C. elegans.
DNA material pEF-FLAG-mouse myosin Vb-tail (RDB15286) Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells.
DNA material pMRX-puro-FLAG-hVPS52 (RDB18998) , pMRX-puro-FLAG-hVPS52_N670 (RDB18999) , pMRX-puro-FLAG-hVPS52_N556 (RDB19000) , pMRX-puro-FLAG-hVPS52_N410 (RDB19001) , pMRX-bsr-ss-sfGFP (RDB19002) Knockout analysis of Rab6 effector proteins revealed the role of VPS52 in the secretory pathway.
Human and Animal Cells RAW 264(RCB0535) Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264 Macrophages.
C.elegans tm2526 , tm2518 Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling.
Human and Animal Cells LY-B(RCB1698) Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole.
DNA material pMRX-bsr-EGFP-P2A-Rab34  (RDB18392) , pEF-FLAG-Rab34-S1A  (RDB18393) , pEF-FLAG-Rab34-deltaN (RDB18394) , pEGFP-C1-Rab34-T66N  (RDB18395) A comprehensive analysis of Rab GTPases reveals a role for Rab34 in serum starvation-induced primary ciliogenesis.
Human and Animal Cells TE-1(RCB1894) , TE-9(RCB1988) , TE-11(RCB2100) , TE-5(RCB1949) High expression of RABL6 promotes cell proliferation and predicts poor prognosis in esophageal squamous cell carcinoma.
Human and Animal Cells ST2(RCB0224) Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells.
DNA material pEGFP-C1-mouse Mon1a (RDB15294) , pEGFP-C1-mouse Ccz1 (RDB15295) Mon1-Ccz1 activates Rab7 only on late endosomes and dissociates from the lysosome in mammalian cells.
DNA material pMRX-bsr-Myc-M-INK (RDB17955) , pMRX-bsr-mCherry-M-INK (RDB17956) , pEGFP-C1-Rab44 (RDB17957) , pEGFP-C1-Rab45 (RDB17958) Rab7B/42 Is Functionally Involved in Protein Degradation on Melanosomes in Keratinocytes.
DNA material pMRX-puro-EGFP-FLCN (RDB17951) , pMRX-puro-EGFP-DENND1A (RDB17952) , pMRX-puro-EGFP-DENND1B (RDB17953) , pMRX-puro-EGFP-DENND1C (RDB17954) Rab35-GEFs, DENND1A and folliculin differentially regulate podocalyxin trafficking in two- and three-dimensional epithelial cell cultures.
C.elegans tm1703 , tm2636 Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding.
C.elegans tm920 , tm1892 , tm1125 , tm592 , tm2241 Function and regulation of the Caenorhabditis elegans Rab32 family member GLO-1 in lysosome-related organelle biogenesis.
Drosophila DGRC#201057 , DGRC#104263 , DGRC#107139 , DGRC#111022 Parcas is the predominant Rab11-GEF for rhodopsin transport in Drosophila photoreceptors.
Drosophila DGRC#109944 , DGRC#109945 Rab11 activation by Ik2 kinase is required for dendrite pruning in Drosophila sensory neurons.
C.elegans tm2523 , tm1447 RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
DNA material pEF-T7-HPS4(S541A/N543A) (RDB17367) , pEF-T7-HPS4(G55W/G59M) (RDB17368) , pEF-FLAG-HPS1 (RDB17369) , pGBD-C1-Rab6D-deltaCys-T45N (RDB17399) , pGBD-C1-Rab40AL-deltaCys-S28N (RDB17444) , pGBD-C1-Rab6D-deltaCys-Q89L (RDB18834) , pGBD-C1-Rab40AL-deltaCys-Q73L (RDB18924) The BLOC-3 subunit HPS4 is required for activation of Rab32/38 GTPases in melanogenesis, but its Rab9 activity is dispensable for melanogenesis.
DNA material pGEX-4T-3-Slac2-b-SHD (RDB17372) Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.