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  • 58 Hits
  • Search Condition : Filter (MeSH = rab GTP-Binding Proteins / metabolism*)
Species Resource
Drosophila DGRC#109944 , DGRC#109945 Rab11 activation by Ik2 kinase is required for dendrite pruning in Drosophila sensory neurons.
C.elegans tm2523 , tm1447 RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
DNA material pGEX-4T-3-Slac2-b-SHD (RDB17372) Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.
Drosophila DGRC#123365 , DGRC#125008 , DGRC#115460 The temporally controlled expression of Drongo, the fruit fly homolog of AGFG1, is achieved in female germline cells via P-bodies and its localization requires functional Rab11.
C.elegans tm2058 , tm2790 , tm2640 , tm3628 , tm3630 , tm2564 , tm1865 , tm2907 The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cells.
C.elegans tm1898 , tm2058 LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
Silkworms p50 Functional characterization of insect-specific RabX6 of Bombyx mori.
C.elegans tm1898 LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts.
C.elegans tm2523 , tm1447 RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
C.elegans tm4024 , tm807 The MADD-3 LAMMER Kinase Interacts with a p38 MAP Kinase Pathway to Regulate the Display of the EVA-1 Guidance Receptor in Caenorhabditis elegans.
C.elegans tm1447 , tm2523 , tm2616 LET-413/Erbin acts as a RAB-5 effector to promote RAB-10 activation during endocytic recycling.
C.elegans tm2095 , tm5384 , tm5654 , tm5694 GOP-1 promotes apoptotic cell degradation by activating the small GTPase Rab2 in C. elegans.
Silkworms p50 Localization and functional analysis of the insect-specific RabX4 in the brain of Bombyx mori.
DNA material pEGFP-C1-mouse Rab20(G64A/C70Y) (RDB15730) , pMRX-bsr-Myc-mouse Rab20-SR (RDB15731). Rab20, a novel Rab small GTPase that negatively regulates neurite outgrowth of PC12 cells.
DNA material pEGFP-C1-human DENN (RDB15288) , pEGFP-C1-mouse DENND1A (RDB15289) , pEGFP-C1-mouse DENND3 (RDB15290). MADD/DENN/Rab3GEP functions as a guanine nucleotide exchange factor for Rab27 during granule exocytosis of rat parotid acinar cells.
DNA material pEF-HA-mouse MICAL-L1 (RDB15385) , pEF-Myc-mouse EHD1 (RDB15386). Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.
DNA material pEF-HA-mouse RILP (RDB15389) , pEF-HA-mouse RILP-L1 (RDB15390) , pEF-HA-mouse RILP-L2 (RDB15391). The Rab interacting lysosomal protein (RILP) homology domain functions as a novel effector domain for small GTPase Rab36: Rab36 regulates retrograde melanosome transport in melanocytes.
DNA material pmStr-N1-mouse Arf6 (RDB15387) , pEGFP-C1-mouse centaurin-b2-N610A/N691A (RDB15384). Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth.
DNA material pEF-T7-mouse Atg5 (RDB15374) , pEF-T7-mouse Atg12 (RDB15375) , pEF-T7-mouse Atg16L1gamma (RDB15376) , pEGFP-C1-mouse Rab33A (RDB15378) , pEGFP-C1-mouse Rab33B (RDB15379) , pEGFP-C1-mouse Rab33B-Q92L (RDB15380) , pEGFP-C1-mouse Rab33B-T47N (RDB15381). Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation.
DNA material pCMV-Mreg delta C/MST-mStr(RDB15184) , pCMV-Mreg delta C/MST-mStr-Rab27A-QL/CA (RDB15185) , pmStr-N1-Mreg (RDB15183). The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through trapping of Rab27A effector protein Slac2-a/melanophilin in their cytosol: development of a novel melanosome-targetinG tag.