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  • 15 Hits
  • Search Condition : Filter (MeSH = rab5 GTP-Binding Proteins / metabolism*)
Species Resource Title
C.elegans tm4536 The exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge.
DNA material pEF-T7-mALS2 (RDB17219) , pEF-T7-mALS2-D1593A (RDB17220). Rab5 activation on macropinosomes requires ALS2, and subsequent Rab5 inactivation through ALS2 detachment requires active Rab7.
C.elegans tm2241 The VPS34 PI3K negatively regulates RAB-5 during endosome maturation.
DNA material pEF-HA-SNAP23-S95E/S120E (RDB15724) , pEF-HA-SNAP23-S95A/S120A (RDB15725). Rab5 is critical for SNAP23 regulated granule-granule fusion during compound exocytosis.
Human and Animal Cells Vinculin and Rab5 complex is required [correction of requited]for uptake of Staphylococcus aureus and interleukin-6 expression.
Yeast FY7520 , FY7251 , FY7132 , FY6767 , FY7643 , FY6873 , FY7085 Coordinated regulation by two VPS9 domain-containing guanine nucleotide exchange factors in small GTPase Rab5 signaling pathways in fission yeast.
Drosophila DGRC#140092 Loss of Rab5 drives non-autonomous cell proliferation through TNF and Ras signaling in Drosophila.
Drosophila Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster.
C.elegans tm2241 TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans.
Drosophila Dynamin- and Rab5-dependent endocytosis is required to prevent Drosophila photoreceptor degeneration.
C.elegans tm2241 C. elegans Rab GTPase activating protein TBC-2 promotes cell corpse degradation by regulating the small GTPase RAB-5.
Drosophila Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes.
C.elegans tm512 A pathway for phagosome maturation during engulfment of apoptotic cells.
C.elegans tm1512 A role for Rab5 in structuring the endoplasmic reticulum.
C.elegans tm1512 Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit.