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  • Search Condition : Filter (MeSH = rac GTP-Binding Proteins / metabolism*)
Species Resource Title
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Human and Animal Cells DT40(RCB1464) , PLC-γ2^(-) DT40(RCB1469) Rac-mediated Stimulation of Phospholipase Cγ2 Amplifies B Cell Receptor-induced Calcium Signaling.
Human and Animal Cells MDCK(RCB0995) Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K.
C.elegans tm4947 The Calponin Family Member CHDP-1 Interacts with Rac/CED-10 to Promote Cell Protrusions.
C.elegans tm514 , tm469 The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac.
C.elegans tm3126 , tm3042. tm403 CACN-1/Cactin interacts genetically with MIG-2 GTPase signaling to control distal tip cell migration in C. elegans.
C.elegans tm2262 RACK-1 acts with Rac GTPase signaling and UNC-115/abLIM in Caenorhabditis elegans axon pathfinding and cell migration.
C.elegans tm1949 , tm1950 Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.
C.elegans tm597 The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.
C.elegans tm6234 , tm5504 SYD-1C, UNC-40 (DCC) and SAX-3 (Robo) function interdependently to promote axon guidance by regulating the MIG-2 GTPase.
Human and Animal Cells ST2(RCB0224) , 10T1/2(RCB0247) Involvement of geranylgeranylation of Rho and Rac GTPases in adipogenic and RANKL expression, which was inhibited by simvastatin.
Human and Animal Cells 293T(RCB2202) Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.
Human and Animal Cells DT40(RCB1464) Nonadherent cells switch to a Rac-mediated, SHIP regulated, Akt activation mode for survival.
Drosophila 4353R-2 The PERK pathway independently triggers apoptosis and a Rac1/Slpr/JNK/Dilp8 signaling favoring tissue homeostasis in a chronic ER stress Drosophila model.
Drosophila DGRC#109572 , DGRC#109575 Synaptic development is controlled in the periactive zones of Drosophila synapses.
Drosophila Niche-associated activation of rac promotes the asymmetric division of Drosophila female germline stem cells.
Drosophila Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye.
Drosophila Activation of Rac1 or Cdc42 during early morphogenesis of eye discs induces ectopic antennae in Drosophila.
Human and Animal Cells C2C12(RCB0987) Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway.
C.elegans tm597 The Arp2/3 activators WAVE and WASP have distinct genetic interactions with Rac GTPases in Caenorhabditis elegans axon guidance.