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Human and Animal Cells KP4(RCB1005) LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
Human and Animal Cells COS-7(RCB0539) Binding of KRH-594, an antagonist of the angiotensin II type 1 receptor, to cloned human and rat angiotensin II receptors.
Human and Animal Cells RAW 264(RCB0535) Irbesartan attenuates production of high-mobility group box 1 in response to lipopolysaccharide via downregulation of interferon-β production.
Human and Animal Cells MRMT-1(RCB2860) P2X7 receptor-mediated analgesia in cancer-induced bone pain.
Human and Animal Cells RAW 264(RCB0535) , THP-1(RCB1189) Cilostazol enhances macrophage reverse cholesterol transport in vitro and in vivo.
Human and Animal Cells PC-12(RCB0009) Neurite outgrowth mediated by translation elongation factor eEF1A1: a target for antiplatelet agent cilostazol.
Rats Olmesartan, a novel AT1 antagonist, suppresses cytotoxic myocardial injury in autoimmune heart failure.