RRC ID 1042
Author Kageyama A, Poonwan N, Yazawa K, Mikami Y, Nishimura K.
Title Nocardia beijingensis, is a pathogenic bacterium to humans: the first infectious cases in Thailand and Japan.
Journal Mycopathologia
Abstract Nocardia beijingensis, a recently established new species, is an isolate from soil in China. During our taxonomic studies on 450 nocardial clinical isolates in Thailand and Japan, 17 strains from Thailand and 1 strain from Japan were found to have a similar physiological characteristic to those of N. beijingensis, such as a drug susceptibility pattern to three antimicrobial agents. Our phylogenetic studies on these 18 strains by 16S rRNA gene sequence analysis confirmed that these strains belong to N. beijingensis species. Phylogenetically, these newly isolated N. beijingensis strains were found to be classified into two distinct clades: one is a Japanese clade and other is a Chinese clade, including a reference strain and 17 Thai strains. This is the first report of human infection due to N. beijingensis strains, and we propose that the bacterium be categorized as an opportunistic infectious group regardless of its original isolation from soil.
Volume 157(2)
Pages 155-61
Published 2004-2
PMID 15119850
MeSH DNA, Bacterial / analysis DNA, Ribosomal / analysis Humans Japan Male Molecular Sequence Data Nocardia / classification* Nocardia / genetics Nocardia / isolation & purification Nocardia / pathogenicity* Nocardia Infections / microbiology* Opportunistic Infections / microbiology Phylogeny RNA, Ribosomal, 16S / genetics Sequence Analysis, DNA Thailand
IF 1.476
Times Cited 21
WOS Category MYCOLOGY
Resource
Pathogenic microorganisms IFM 0460 IFM 0510 IFM 0517 IFM 0537 IFM 0542 IFM 0560 IFM 0693 IFM 0694 IFM 0722 IFM 0728 IFM 0732 IFM 0841 IFM 0846 IFM 0847 IFM 0908 IFM 0915 IFM 10052 IFM 10100 IFM 10174