RRC ID 1053
Author Myoken Y, Kyo T, Fujihara M, Sugata T, Mikami Y.
Title Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic malignancies.
Journal Haematologica
Abstract A 5-year retrospective analysis of fungemia in patients with hematologic malignancies revealed that four patients, who received fluconazole and itraconazole during neutropenia, developed breakthrough candidemia due to azole-resistant Candida tropicalis isolates. This observation suggests that causative organisms of candidemia in neutropenic patients receiving azoles should be suspected of being azole-resistant.
Volume 89(3)
Pages 378-80
Published 2004-3
PMID 15020289
MeSH Adult Aged Antifungal Agents / therapeutic use* Azoles / therapeutic use* Candida tropicalis / drug effects* Candidiasis / drug therapy Candidiasis / microbiology* Drug Resistance, Microbial Female Fungemia / drug therapy Fungemia / microbiology* Hematologic Neoplasms / immunology* Hematologic Neoplasms / microbiology Humans Male Middle Aged Neutropenia / complications Retrospective Studies
IF 9.09
Times Cited 14
Pathogenic microorganisms C. tropicalis?