Reference - Detail
| RRC ID | 1093 |
|---|---|
| Author | Okamoto S, Hosoe T, Itabashi T, Nozawa K, Okada K, Takaki GM, Chikamori M, Yaguchi T, Fukushima K, Miyaji M, Kawai K. |
| Title | New decalin derivatives, eujavanoic acids A and B, from Eupenicillium javanicum. |
| Journal | J Nat Prod |
| Abstract |
Two new decalin derivatives, eujavanoic acids A (1) and B (2), were isolated from Eupenicillium javanicum, along with several compactin derivatives. The structures of 1 and 2 were determined by spectroscopic methods and modified Mosher's method. The side chain (2-methylbutanoyloxy) and acid functionalities of compactin derivatives were necessary to show the antifungal activity. |
| Volume | 67(9) |
| Pages | 1580-3 |
| Published | 2004-9-1 |
| DOI | 10.1021/np040052s |
| PMID | 15387665 |
| MeSH | Antifungal Agents / chemistry Antifungal Agents / isolation & purification* Antifungal Agents / pharmacology Ascomycota / chemistry* Aspergillus fumigatus / drug effects Candida albicans / drug effects Cryptococcus neoformans / drug effects Lovastatin / analogs & derivatives* Lovastatin / chemistry Lovastatin / pharmacology Molecular Conformation Molecular Structure Naphthalenes / chemistry Naphthalenes / isolation & purification* Naphthalenes / pharmacology |
| IF | 3.782 |
| Times Cited | 6 |
| WOS Category | PLANT SCIENCES PHARMACOLOGY & PHARMACY CHEMISTRY, MEDICINAL |
| Resource | |
| Pathogenic microorganisms | E. javanicum? IFM 52670 |