| RRC ID |
11002
|
| 著者 |
Tung NH, Ding Y, Choi EM, Minh CV, Kim YH.
|
| タイトル |
New neolignan component from Camellia amplexicaulis and effects on osteoblast differentiation.
|
| ジャーナル |
Chem Pharm Bull (Tokyo)
|
| Abstract |
A new neolignan named "camellioside A" (1) has been isolated from the leaves and branches of Camellia amplexicaulis, along with seven known glycosides (2-8). Their structures were determined by a variety of spectroscopic analyses. Among them, compounds 2, 3, 4, and 6 significantly (p<0.05) increased the alkaline phosphatase activity and the mineralization of the nodules of the MC3T3-E1 osteoblastic cells compared to those of the control.
|
| 巻・号 |
57(1)
|
| ページ |
65-8
|
| 公開日 |
2009-1-1
|
| DOI |
10.1248/cpb.57.65
|
| PII |
JST.JSTAGE/cpb/57.65
|
| PMID |
19122318
|
| MeSH |
Animals
Camellia*
Cell Differentiation
Cell Line
Lignans / chemistry
Lignans / pharmacology*
Mice
Mice, Inbred C57BL
Molecular Structure
Osteoblasts / drug effects*
Osteogenesis / drug effects
Plant Components, Aerial*
Plant Extracts / chemistry
Plant Extracts / pharmacology*
|
| IF |
1.416
|
| 引用数 |
9
|
|
WOS 分野
|
CHEMISTRY, MULTIDISCIPLINARY
PHARMACOLOGY & PHARMACY
CHEMISTRY, MEDICINAL
|
| リソース情報 |
| ヒト・動物細胞 |
MC3T3-E1(RCB1126) |
