RRC ID 1143
Author Kawamura Y, Itoh Y, Mishima N, Ohkusu K, Kasai H, Ezaki T.
Title High genetic similarity of Streptococcus agalactiae and Streptococcus difficilis: S. difficilis Eldar et al. 1995 is a later synonym of S. agalactiae Lehmann and Neumann 1896 (Approved Lists 1980).
Journal Int. J. Syst. Evol. Microbiol.
Abstract The genetic relationship between Streptococcus agalactiae and Streptococcus difficilis was studied. S. difficilis was originally described as serologically non-typable but was later reported to be a group B, type Ib streptococcus. Upon comparative analysis of five gene sequences, it was found that S. agalactiae and S. difficilis are closely related. Sequence similarity values between these two species were 100.0 % for 16S rRNA, 99.6 % for gyrB, 98.6 % for sodA, 99.5 % for gyrA and 99.8 % for parC genes. These data strongly suggest that S. agalactiae and S. difficilis are synonyms. The biochemical characteristics of S. difficilis, which differ slightly from those of typical S. agalactiae, are similar to those of other group B, type Ib streptococci isolated from fish and frogs. Whole genome DNA-DNA hybridization values between the type strains of both species were greater than 78.6 %. On the basis of these data, it is proposed that S. difficilis is a later synonym of S. agalactiae.
Volume 55(Pt 2)
Pages 961-5
Published 2005-3
DOI 10.1099/ijs.0.63403-0
PII 55/2/961
PMID 15774692
MeSH Animals Bacterial Proteins / genetics DNA Gyrase / genetics DNA Topoisomerase IV / genetics DNA, Bacterial / analysis Humans Molecular Sequence Data Nucleic Acid Hybridization Phylogeny RNA, Ribosomal, 16S / genetics Sequence Analysis, DNA Streptococcus / classification* Streptococcus / genetics Streptococcus agalactiae / classification* Streptococcus agalactiae / genetics Superoxide Dismutase / genetics
IF 1.932
Times Cited 22
Pathogenic microorganisms GTC 00730 GTC 00423 GTC 00262 GTC 01234 GTC 00431 GTC 00842 GTC 00269 GTC 00542 GTC 00244 GTC 00543 GTC 00539 GTC 00271 GTC 02049