RRC ID |
1159
|
著者 |
Teixeira AB, Silva M, Lyra L, Luz EA, Uno J, Takada H, Miyaji M, Nishimura K, Schreiber AZ.
|
タイトル |
Antifungal susceptibility and pathogenic potential of environmental isolated filamentous fungi compared with colonizing agents in immunocompromised patients.
|
ジャーナル |
Mycopathologia
|
Abstract |
Infection is a major cause of morbidity and mortality in bone marrow transplant recipients and in patients with hematological malignancies. The source of infection is almost always endogenous flora or the hospital environment. The present study evaluated bone marrow transplant recipients and patients with hematological malignancies colonized and/or infected with filamentous fungi. During 1 year, environmental air samples were also taken from the bone marrow transplant unit by a modification of gravity air-setting plate (GASP) methodology. Fusarium spp. were the most prevalent genus in the fall and Cladosporium spp. in the winter. Clinically isolated strains grew better at 37 degrees C than environmental strains. According to NCCLS M-38P methods, environmental Aspergillus strains showed higher MICs to miconazol and itraconazol, and clinical Fusarium strains were less susceptible to fluconazole.
|
巻・号 |
160(2)
|
ページ |
129-35
|
公開日 |
2005-9-1
|
DOI |
10.1007/s11046-005-0117-z
|
PMID |
16170608
|
MeSH |
Air Microbiology*
Antifungal Agents / pharmacology*
Aspergillus / drug effects
Aspergillus / isolation & purification
Aspergillus / pathogenicity
Bone Marrow Transplantation / adverse effects
Cladosporium / drug effects
Cladosporium / isolation & purification
Cladosporium / pathogenicity
Fusarium / drug effects
Fusarium / isolation & purification
Fusarium / pathogenicity
Hematologic Neoplasms / complications
Hospitals, Teaching
Humans
Immunocompromised Host*
Microbial Sensitivity Tests
Mitosporic Fungi / classification
Mitosporic Fungi / drug effects*
Mitosporic Fungi / isolation & purification
Mitosporic Fungi / pathogenicity*
Mycoses / microbiology*
|
IF |
2.452
|
引用数 |
7
|
WOS 分野
|
MYCOLOGY
|
リソース情報 |
病原微生物 |
IFM 5774
IFM 40205
IFM 46829
Fusarium spp. ?
Cladosporium spp.?
Aspergillus? |