RRC ID 11625
Author Ryuda M, Tsuzuki S, Tanimura T, Tojo S, Hayakawa Y.
Title A gene involved in the food preferences of larval Drosophila melanogaster.
Journal J Insect Physiol
Abstract To examine the mechanism by which insects change their food preferences, a simple method was developed to measure their preferences. By using this method, we demonstrated preference of Drosophila melanogaster larvae of the yw control strain for a food based on soybeans over one based on cornmeal. We then screened for mutant strains with food preferences clearly different from the control yw strain, using the Gene Search collection of P-element insertions (GS strains). Among 380 GS strains screened using an assay plate-containing soybean and corn tastants, we identified one mutant, GS1189 that did not show any preference for either of the foods. Further behavioral assays indicated that the GS1189 larvae could have impaired olfactory and gustatory systems. The fact that the CG33071 gene expression was inactivated by the P-element insertion in the GS1189 strain, and that reversion of this gene completely recovered the normal food preference, indicates that this gene contributes to the control of food preferences in Drosophila larvae.
Volume 54(10-11)
Pages 1440-5
Published 2008-10-1
DOI 10.1016/j.jinsphys.2008.08.006
PII S0022-1910(08)00162-5
PMID 18773904
MeSH Animals Brain / physiology DNA Transposable Elements / genetics Drosophila melanogaster / genetics Drosophila melanogaster / physiology* Food Preferences / physiology* Larva / genetics Larva / physiology Mutagenesis, Insertional RNA / chemistry RNA / genetics Reverse Transcriptase Polymerase Chain Reaction Smell / physiology
IF 2.246
Times Cited 11
WOS Category ENTOMOLOGY ZOOLOGY PHYSIOLOGY
Resource
Drosophila GS strains