| RRC ID |
11660
|
| Author |
Ichikawa A, Yamada A, Sakamoto H, Umehara M, Yoshioka Y, Yamaguchi M, Ikura K.
|
| Title |
Overexpression of transglutaminase in the Drosophila wing imaginal disc induced an extra wing crossvein phenotype.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
To determine the roles of Drosophila transglutaminase-A (dTG-A), we examined a phenotype induced through ectopic expression of dTG-A. Overexpression of dTG-A in the wing imaginal disc induced an extra wing crossvein phenotype. This phenotype was suppressed by crossing with epidermal growth factor receptor (Egfr) signaling pathway mutant flies. These results indicate that this phenotype, induced by dTG-A, is related to enhancement of the Egfr signaling pathway.
|
| Volume |
74(12)
|
| Pages |
2494-6
|
| Published |
2010-12-7
|
| DOI |
10.1271/bbb.100449
|
| PII |
JST.JSTAGE/bbb/100449
|
| PMID |
21150110
|
| MeSH |
Animals
Drosophila melanogaster / anatomy & histology*
Drosophila melanogaster / enzymology*
Drosophila melanogaster / genetics
Gene Expression
Phenotype*
Transglutaminases / genetics*
Wings, Animal / anatomy & histology*
Wings, Animal / enzymology*
|
| IF |
1.516
|
| Times Cited |
5
|
|
WOS Category
|
FOOD SCIENCE & TECHNOLOGY
CHEMISTRY, APPLIED
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
| Resource |
| Drosophila |
|
