| RRC ID |
1167
|
| Author |
Hattori N, Shirai A, Sugiura Y, Li W, Yokoyama K, Misawa Y, Okuzumi K, Tamaki K.
|
| Title |
Onychomycosis caused by Fusarium proliferatum.
|
| Journal |
Br J Dermatol
|
| Abstract |
Fusarium infections in humans are usually opportunistic, but the fungus sometimes infects healthy persons, causing keratomycosis or onychomycosis. Onychomycosis is usually caused by F. solani or F. oxysporum. We report the first two cases of onychomycosis caused by F. proliferatum, and discuss methods of diagnosis and effective treatment. Nail samples from the two patients were examined by direct microscopy, cultured, and identified morphologically and genetically as F. proliferatum. Both patients were treated successfully with oral itraconazole, even though the minimum inhibitory concentration of itraconazole was relatively high in Patient 1. This is the first report of F. proliferatum as an agent of onychomycosis. Itraconazole may be effective in the treatment of onychomycosis caused by F. proliferatum.
|
| Volume |
153(3)
|
| Pages |
647-9
|
| Published |
2005-9-1
|
| DOI |
10.1111/j.1365-2133.2005.06692.x
|
| PII |
BJD6692
|
| PMID |
16120158
|
| MeSH |
Antifungal Agents / therapeutic use
Foot Dermatoses / drug therapy
Foot Dermatoses / microbiology*
Fusarium* / genetics
Genes, Fungal
Hand Dermatoses / drug therapy
Hand Dermatoses / microbiology*
Humans
Itraconazole / therapeutic use
Japan
Male
Middle Aged
Onychomycosis / drug therapy
Onychomycosis / microbiology*
Pulse Therapy, Drug
Sequence Analysis, DNA
|
| IF |
7.0
|
| Times Cited |
20
|
|
WOS Category
|
DERMATOLOGY
|
| Resource |
| Pathogenic microorganisms |
F. solani?
F. oxysporum?
F. proliferatum? |
