| RRC ID |
1169
|
| Author |
Teixeira AB, Moretti ML, Trabasso P, von Nowakonski A, Aoki FH, Vigorito AC, Miyaji M, Nishimura K, Taguchi H, Schreiber AZ.
|
| Title |
Evaluation of Fusarium solani hyphae and conidia susceptibility to amphotericin B and itraconazole: study of a clinical case.
|
| Journal |
Mycopathologia
|
| Abstract |
Fusarium species are hyaline moulds belonging to the hyalohyphomycosis group that are usually found in the soil and plants. This organism has emerged as a cause of disseminated invasive disease. The correlation between in vitro value and clinical efficacy is low and many patients remain unresponsive to treatment despite in vitro susceptibility. We determined growth control for Fusarium solani using the BioCell-Tracer system that measures the growth rate of a single fungal hypha, and the effect of different concentrations of amphotericin B and itraconazole. The MIC for these two drugs was also determined by a broth microdilution technique, using RPMI 1640. Different MICs for amphotericin B were obtained by the two different methods. This paper describes a case of infection due to Fusarium solani in an allogeneic bone marrow transplanted patient, the microbiological diagnostic, antifungal susceptibility tests for conidia and hypha and clinical correlation.
|
| Volume |
160(4)
|
| Pages |
291-6
|
| Published |
2005-11-1
|
| DOI |
10.1007/s11046-005-0106-2
|
| PMID |
16244897
|
| MeSH |
Adult
Amphotericin B / pharmacology*
Amphotericin B / therapeutic use
Antifungal Agents / pharmacology*
Antifungal Agents / therapeutic use
Bone Marrow Transplantation / adverse effects
DNA, Fungal / chemistry
DNA, Fungal / genetics
Fatal Outcome
Female
Fusarium / drug effects*
Fusarium / growth & development
Fusarium / isolation & purification
Humans
Immunocompromised Host
Mycoses / drug therapy
Mycoses / microbiology*
Pregnancy
Pregnancy Complications, Infectious / microbiology
Sepsis / drug therapy
Sepsis / microbiology*
|
| IF |
2.452
|
| Times Cited |
6
|
|
WOS Category
|
MYCOLOGY
|
| Resource |
| Pathogenic microorganisms |
F. solani? |
