RRC ID |
1170
|
Author |
Komai S, Hosoe T, Itabashi T, Nozawa K, Okada K, Campos Takaki GM, Yaguchi T, Takizawa K, Fukushima K, Kawai K.
|
Title |
Two new meroterpenoids, penisimplicin A and B, isolated from Penicillium simplicissimum.
|
Journal |
Chem Pharm Bull (Tokyo)
|
Abstract |
In the course of our research for new antifungal agents, two new meroterpenoids, penisimplicin A (1) and B (2), were isolated from Penicillium simplicissimum. The absolute structures of 1 and 2 were established by spectroscopic and chemical investigation. Penisimplicin A (1) and B (2) are rare examples of D-ring seco-meroterpenoids. Since compounds 1 and 2 showed no antifungal activities, the isolation of the compounds with antifungal activity will be attempted.
|
Volume |
53(9)
|
Pages |
1114-7
|
Published |
2005-9-1
|
DOI |
10.1248/cpb.53.1114
|
PII |
JST.JSTAGE/cpb/53.1114
|
PMID |
16141578
|
MeSH |
Antifungal Agents / chemistry*
Borohydrides
Carbohydrate Conformation
Chromatography, High Pressure Liquid
Crystallography, X-Ray
Hydrolysis
Indicators and Reagents
Magnetic Resonance Spectroscopy
Methanol
Penicillium / chemistry*
|
IF |
1.416
|
Times Cited |
9
|
WOS Category
|
CHEMISTRY, MULTIDISCIPLINARY
PHARMACOLOGY & PHARMACY
CHEMISTRY, MEDICINAL
|
Resource |
Pathogenic microorganisms |
IFM 40009
IFM 41243
IFM 53375 |