RRC ID |
11951
|
Author |
Hikosaka A, Nishimura K, Hikosaka-Katayama T, Kawahara A.
|
Title |
Recent transposition activity of Xenopus T2 family miniature inverted-repeat transposable elements.
|
Journal |
Mol Genet Genomics
|
Abstract |
To investigate the recent transposition activity of T2 family miniature inverted-repeat transposable elements (MITEs) in Xenopus tropicalis (Western clawed frog), we analyzed the intraspecific polymorphisms associated with MITE insertion in X. tropicalis for three subfamilies of the T2 family (T2-A1, T2-C, and T2-E). A high frequency of MITE-insertion polymorphisms was observed at the T2-A1 (50%) and T2-C insertion loci (60%), but none were noted at the T2-E insertion locus (0%). Analyses of the collected data indicated that members of the T2-A1 and T2-C subfamilies may be currently active in the host species. Identification of these active transpositions will help us in understanding the mechanisms underlying the long-term survival (over several tens of millions of years) of the T2-A1 and T2-C subfamilies.
|
Volume |
285(3)
|
Pages |
219-24
|
Published |
2011-3-1
|
DOI |
10.1007/s00438-010-0599-3
|
PMID |
21234602
|
MeSH |
Animals
Base Sequence
DNA Primers / genetics
DNA Transposable Elements / genetics*
Evolution, Molecular*
Inverted Repeat Sequences / genetics*
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic / genetics*
Sequence Analysis, DNA
Xenopus / genetics*
|
IF |
2.797
|
Times Cited |
6
|
WOS Category
|
GENETICS & HEREDITY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
Resource |
Clawed frogs / Newts |
|