RRC ID 11951
Author Hikosaka A, Nishimura K, Hikosaka-Katayama T, Kawahara A.
Title Recent transposition activity of Xenopus T2 family miniature inverted-repeat transposable elements.
Journal Mol Genet Genomics
Abstract To investigate the recent transposition activity of T2 family miniature inverted-repeat transposable elements (MITEs) in Xenopus tropicalis (Western clawed frog), we analyzed the intraspecific polymorphisms associated with MITE insertion in X. tropicalis for three subfamilies of the T2 family (T2-A1, T2-C, and T2-E). A high frequency of MITE-insertion polymorphisms was observed at the T2-A1 (50%) and T2-C insertion loci (60%), but none were noted at the T2-E insertion locus (0%). Analyses of the collected data indicated that members of the T2-A1 and T2-C subfamilies may be currently active in the host species. Identification of these active transpositions will help us in understanding the mechanisms underlying the long-term survival (over several tens of millions of years) of the T2-A1 and T2-C subfamilies.
Volume 285(3)
Pages 219-24
Published 2011-3-1
DOI 10.1007/s00438-010-0599-3
PMID 21234602
MeSH Animals Base Sequence DNA Primers / genetics DNA Transposable Elements / genetics* Evolution, Molecular* Inverted Repeat Sequences / genetics* Molecular Sequence Data Polymerase Chain Reaction Polymorphism, Genetic / genetics* Sequence Analysis, DNA Xenopus / genetics*
IF 2.797
Times Cited 6
WOS Category GENETICS & HEREDITY BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
Clawed frogs / Newts