RRC ID 137
著者 Kon H, Tohei A, Hokao R, Shinoda M.
タイトル Estrous cycle stage-independent treatment of PMSG and hCG can induce superovulation in adult Wistar-Imamichi rats.
ジャーナル Exp Anim
Abstract The estrous cycle influence on the number of ovulated eggs after injection of pregnant mare serum gonadotropin (PMSG) and human chorionic gonadotropin (hCG) was investigated in 12, 18, and 24 weeks old adult female Wistar-Imamichi (WI) rats. PMSG (150 IU/kg) was injected at metestrus, diestrus, proestrus, or estrus, followed by hCG (75 IU/kg) 55 h later. Ovulation was induced at all ages and stages of the estrous cycle. The number of ovulated eggs was not affected by stage for similarly aged rats, however, the number of ovulated eggs obtained after treatment decreased with age. These results demonstrate that the PMSG/hCG treatment can induce ovulation at any stage of estrous cycle in WI rats and efficient superovulation at 12 weeks of age.
巻・号 54(2)
ページ 185-7
公開日 2005-4-1
DOI 10.1538/expanim.54.185
PII JST.JSTAGE/expanim/54.185
PMID 15897629
MeSH Aging / physiology Animals Chorionic Gonadotropin / administration & dosage Chorionic Gonadotropin / pharmacology* Estrous Cycle / physiology* Female Gonadotropins, Equine / administration & dosage Gonadotropins, Equine / pharmacology* Injections, Intraperitoneal Rats Rats, Wistar Stimulation, Chemical Superovulation / drug effects*
IF 1.574
引用数 13
WOS 分野 VETERINARY SCIENCES ZOOLOGY
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