Reference - Detail
| RRC ID | 15418 |
|---|---|
| Author | Akiyama K, Maruyama M, Yamauchi S, Nakashima Y, Nakato T, Tago R, Sugahara T, Kishida T, Koba Y. |
| Title | Antimicrobiological activity of lignan: effect of benzylic oxygen and stereochemistry of 2,3-dibenzyl-4-butanolide and 3,4-dibenzyltetrahydrofuran lignans on activity. |
| Journal | Biosci Biotechnol Biochem |
| Abstract |
The effect of oxidation degree at the benzylic position of 2,3-dibenzyl-4-butanolide and 3,4-dibenzyltetrahydrofuran lignans on the antimicrobiological activity was examined. The highest oxidation degree at the benzylic position of 2,3-dibenzyl-4-butanolide gave the greatest activity, and 3,4-dibenzoyltetrahydrofuran showed the highest antifungal activity. The relationship between stereochemistry and activity was also examined. Both enantiomers of cis-matairesinol were synthesized for the first time, one of the cis-matairesinols showing antibacterial activity. |
| Volume | 71(7) |
| Pages | 1745-51 |
| Published | 2007-7-1 |
| DOI | 10.1271/bbb.70168 |
| PII | JST.JSTAGE/bbb/70168 |
| PMID | 17617715 |
| MeSH | 4-Butyrolactone / chemistry 4-Butyrolactone / pharmacology Anti-Infective Agents / chemistry Anti-Infective Agents / pharmacology* Bacillus subtilis / drug effects Furans / chemistry Furans / pharmacology* Lignans / chemistry Lignans / pharmacology* Molecular Conformation Oxygen / chemistry* Pseudomonas fluorescens / drug effects Staphylococcus aureus / drug effects Structure-Activity Relationship |
| IF | 1.516 |
| Times Cited | 24 |
| WOS Category | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
|
| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| General Microbes | JCM 1649 JCM 6977 JCN 7579 JCM 11481 |