RRC ID 15441
Author Yamada-Onodera K, Norimoto A, Kawada N, Furuya R, Yamamoto H, Tani Y.
Title Production of optically active 1,2,4-butanetriol from corresponding racemate by Microbial stereoinversion.
Journal J Biosci Bioeng
Abstract Sterigmatomyces elviae DSM 70852 produced 12 g/l (S)-1,2,4-butanetriol (enantiomeric excess >99.9%) from 20 g/l racemate in 82 h. From the results of the inversion of an (R)-isomer to an (S)-isomer and GC-MS, it was suggested that (R)-1,2,4-butanetriol is oxidized to 1,4-dihydroxy-2-butanone, which is reduced to an (S)-isomer.
Volume 103(5)
Pages 494-6
Published 2007-5-1
DOI 10.1263/jbb.103.494
PII S1389-1723(07)70094-4
PMID 17609168
MeSH Butanols / chemistry* Butanols / isolation & purification* Oxidation-Reduction Stereoisomerism Streptomyces / metabolism*
IF 2.366
Times Cited 10
WOS Category FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Resource
General Microbes JCM 1747 JCM 2467 JCM 5222