RRC ID 15620
Author Ito S, Narise A, Shimura S.
Title Identification of a methioninase inhibitor, myrsinoic acid B, from Myrsine seguinii Lév., and its inhibitory activities.
Journal Biosci Biotechnol Biochem
Abstract A methioninase inhibitor from Myrsine seguinii was purified and identified as myrsinoic acid B. Its inhibitory activities as to crude methioninase from periodontal bacteria such as Fusobacterium nucleatum, Porphyromonas gingivalis, and Treponema denticola were determined. The IC50 values were 10.5, 82.4, and 30.3 microM respectively.
Volume 72(9)
Pages 2411-4
Published 2008-9-1
DOI 10.1271/bbb.80045
PII JST.JSTAGE/bbb/80045
PMID 18776663
MeSH Alkenes / chemistry* Alkenes / isolation & purification Alkenes / pharmacology* Benzofurans / chemistry* Benzofurans / isolation & purification Benzofurans / pharmacology* Butyrates / antagonists & inhibitors Carbon-Sulfur Lyases / antagonists & inhibitors* Fusobacterium nucleatum / metabolism Inhibitory Concentration 50 Methylmercury Compounds / antagonists & inhibitors Molecular Structure Periodontitis / microbiology Porphyromonas gingivalis / metabolism Primulaceae / chemistry* Species Specificity Treponema denticola / metabolism
IF 1.516
Times Cited 11
WOS Category FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
General Microbes JCM 8532