Reference - Detail
| RRC ID | 15641 |
|---|---|
| Author | Kitagawa W, Tamura T. |
| Title | A quinoline antibiotic from Rhodococcus erythropolis JCM 6824. |
| Journal | J Antibiot (Tokyo) |
| Abstract |
A new quinoline antibiotic, aurachin RE, was isolated and identified from a culture broth of Rhodococcus erythropolis JCM 6824. The aurachin RE structure was determined based on NMR and mass spectrometric analysis. The structure is similar to that of aurachin C antibiotics that have been identified from Stigmatella aurantiaca. Compared to aurachin C, however, aurachin RE exhibits a wide and strong antimicrobial spectrum against both high- and low-GC Gram-positive bacteria. |
| Volume | 61(11) |
| Pages | 680-2 |
| Published | 2008-11-1 |
| DOI | 10.1038/ja.2008.96 |
| PII | JST.JSTAGE/antibiotics/61.680 |
| PMID | 19168983 |
| MeSH | Anti-Bacterial Agents / chemistry Anti-Bacterial Agents / isolation & purification* Anti-Bacterial Agents / pharmacology* Culture Media / chemistry* Gram-Positive Bacteria / drug effects Hydroxylamines / chemistry Hydroxylamines / isolation & purification* Hydroxylamines / pharmacology* Magnetic Resonance Spectroscopy Mass Spectrometry Microbial Sensitivity Tests Molecular Structure Quinolones / chemistry Quinolones / isolation & purification* Quinolones / pharmacology* Rhodococcus / growth & development Rhodococcus / metabolism* |
| IF | 2.668 |
| Times Cited | 32 |
| WOS Category | PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY IMMUNOLOGY MICROBIOLOGY |
| Resource | |
| General Microbes | JCM 6824 |