RRC ID 15707
Author Tanaka K, Mikamo H, Nakao K, Ichiishi T, Goto T, Yamagishi Y, Watanabe K.
Title In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria.
Journal Antimicrob Agents Chemother
Abstract The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with other carbapenems. Tomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC(90), 0.06 to 4 microg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem.
Volume 53(1)
Pages 319-22
Published 2009-1-1
DOI 10.1128/AAC.00595-08
PII AAC.00595-08
PMID 18955522
PMC PMC2612141
MeSH Anti-Bacterial Agents / pharmacology* Bacteria, Anaerobic / drug effects* Carbapenems / pharmacology* Doripenem Meropenem Microbial Sensitivity Tests Thienamycins / pharmacology
IF 4.904
Times Cited 9
WOS Category PHARMACOLOGY & PHARMACY MICROBIOLOGY
Resource
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