Reference - Detail
| RRC ID | 15721 |
|---|---|
| Author | Kawaguchi Y, Yamauchi S, Masuda K, Nishiwaki H, Akiyama K, Maruyama M, Sugahara T, Kishida T, Koba Y. |
| Title | Antimicrobial activity of stereoisomers of butane-type lignans. |
| Journal | Biosci Biotechnol Biochem |
| Abstract |
The relationship between the stereochemistry and antimicrobial activity of butane-type lignans was clarified. All stereoisomers of dihydroguaiaretic acid (DGA) showed both antibacterial and antifungal activity. The (+)- and (-)-7,7'-dioxodihydroguaiaretic acid (ODGA) also showed both antibacterial and antifungal activity, while meso-ODGA did not show antibacterial activity, but showed antifungal activity. No activity of any stereoisomer of secoisolariciresinol (SECO) was apparent. |
| Volume | 73(8) |
| Pages | 1806-10 |
| Published | 2009-8-1 |
| DOI | 10.1271/bbb.90167 |
| PII | JST.JSTAGE/bbb/90167 |
| PMID | 19661689 |
| MeSH | Anti-Infective Agents / chemical synthesis Anti-Infective Agents / chemistry* Anti-Infective Agents / pharmacology* Bacteria / drug effects Butanes / chemistry* Foodborne Diseases / microbiology Fungi / drug effects Guaiacol / analogs & derivatives* Guaiacol / chemical synthesis Guaiacol / chemistry Guaiacol / pharmacology Lignans / chemical synthesis Lignans / chemistry* Lignans / pharmacology* Plant Diseases / microbiology Stereoisomerism Structure-Activity Relationship Substrate Specificity |
| IF | 1.516 |
| Times Cited | 21 |
| WOS Category | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Resource | |
| General Microbes | JCM 1649 JCM 6977 JCM 7579 JCM 11481 |