論文 - 詳細
| RRC ID | 15824 |
|---|---|
| 著者 | Hashimoto M, Katsura H, Kato R, Kawaide H, Natsume M. |
| タイトル | Effect of pamamycin-607 on secondary metabolite production by Streptomyces spp. |
| ジャーナル | Biosci Biotechnol Biochem |
| Abstract |
The effect of the aerial mycelium-inducing compound, pamamycin-607, on antibiotic production by several Streptomyces spp. was examined. Exposure to 6.6 µM pamamycin-607 stimulated by 2.7 fold the puromycin production by Streptomyces alboniger NBRC 12738, in which pamamycin-607 had first been isolated, and restored aerial mycelium formation. Pamamycin-607 also stimulated the respective production of streptomycin by S. griseus NBRC 12875 and that of cinerubins A and B by S. tauricus JCM 4837 by approximately 1.5, 1.7 and 1.9 fold. The antibiotic produced by Streptomyces sp. 91-a was identified as virginiamycin M(1), and its synthesis was enhanced 2.6 fold by pamamycin-607. These results demonstrate that pamamycin-607 not only restored or stimulated aerial mycelium formation, but also stimulated secondary metabolite production. |
| 巻・号 | 75(9) |
| ページ | 1722-6 |
| 公開日 | 2011-1-1 |
| DOI | 10.1271/bbb.110251 |
| PII | JST.JSTAGE/bbb/110251 |
| PMID | 21897037 |
| MeSH | Anti-Bacterial Agents / biosynthesis* Anti-Bacterial Agents / isolation & purification Chromatography, High Pressure Liquid Macrolides / pharmacology* Mycelium* / drug effects Mycelium* / physiology Staphylococcus aureus / drug effects Staphylococcus aureus / growth & development Streptomyces* / drug effects Streptomyces* / physiology Streptomycin / biosynthesis* Streptomycin / isolation & purification |
| IF | 1.516 |
| 引用数 | 10 |
| WOS 分野 | FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY |
| リソース情報 | |
| 一般微生物 | JCM 4837 |