Reference - Detail
| RRC ID | 17456 |
|---|---|
| Author | Furuhata K, Ogihara K, Ishizaki N, Oonaka K, Yoshida Y, Goto K, Hara M, Miyamoto H, Yoshida S, Fukuyama M. |
| Title | Identification of Legionella londiniensis isolated from hot spring water samples in Shizuoka, Japan, and cytotoxicity of isolates. |
| Journal | J Infect Chemother |
| Abstract |
As part of an epidemiological study on legionellosis, we attempted to isolate Legionella spp. from hot spring water and were able to isolate L. londiniensis HYKF-90505 (=JCM 16338), confirming that L. londiniensis inhabits hot spring water in Japan. To investigate the disease potential of L. londiniensis, we examined its ability to grow intracellularly within Acanthamoeba sp. JAC/E1 strain. The isolated HYKF-90505 was able to grow within Acanthamoeba sp. JAC/E1 strain, and we confirmed also that the HYKF-90505 strain showed cytotoxicity for cultured cells such as J774.1 (JCRB0018). However, in a culture of human U937 cells, the bacterial count was not increased by the intracellular growth of the HYKF-90505 strain. Cells infected for 24 h and stained using the Giménez method showed no intracellular growth of the HYKF-90505 strain. Thus, the isolate appears to be weakly pathogenic to humans. |
| Volume | 16(5) |
| Pages | 367-71 |
| Published | 2010-10-1 |
| DOI | 10.1007/s10156-010-0062-8 |
| PII | S1341-321X(10)70585-7 |
| PMID | 20419328 |
| MeSH | Acanthamoeba / microbiology Hot Springs / microbiology* Humans Intracellular Space / microbiology Japan Legionella / isolation & purification* Legionella / pathogenicity U937 Cells Water Microbiology |
| IF | 1.722 |
| Times Cited | 8 |
| WOS Category | PHARMACOLOGY & PHARMACY INFECTIOUS DISEASES |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Wikipedia |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| General Microbes | JCM 16338 |