RRC ID 17514
Author Tanji J, Hoshi E.
Title Role of the lateral prefrontal cortex in executive behavioral control.
Journal Physiol Rev
Abstract The lateral prefrontal cortex is critically involved in broad aspects of executive behavioral control. Early studies emphasized its role in the short-term retention of information retrieved from cortical association areas and in the inhibition of prepotent responses. Recent studies of subhuman primates and humans have revealed the role of this area in more general aspects of behavioral planning. Novel findings of neuronal activity have specified how neurons in this area take part in selective attention for action and in selecting an intended action. Furthermore, the involvement of the lateral prefrontal cortex in the implementation of behavioral rules and in setting multiple behavioral goals has been discovered. Recent studies have begun to reveal neuronal mechanisms for strategic behavioral planning and for the development of knowledge that enables the planning of macrostructures of event-action sequences at the conceptual level.
Volume 88(1)
Pages 37-57
Published 2008-1-1
DOI 10.1152/physrev.00014.2007
PII 88/1/37
PMID 18195082
MeSH Animals Behavior, Animal / physiology* Cognition / physiology* Concept Formation / physiology Decision Making / physiology Humans Memory / physiology Prefrontal Cortex / physiology*
IF 25.588
Times Cited 266
WOS Category PHYSIOLOGY
Resource
Japanese macaques