論文 - 詳細
| RRC ID | 1824 |
|---|---|
| 著者 | Perrimon N, Mathey-Prevot B. |
| タイトル | Applications of high-throughput RNA interference screens to problems in cell and developmental biology. |
| ジャーナル | Genetics |
| Abstract |
RNA interference (RNAi) in tissue culture cells has emerged as an excellent methodology for identifying gene functions systematically and in an unbiased manner. Here, we describe how RNAi high-throughput screening (HTS) in Drosophila cells are currently being performed and emphasize the strengths and weaknesses of the approach. Further, to demonstrate the versatility of the technology, we provide examples of the various applications of the method to problems in signal transduction and cell and developmental biology. Finally, we discuss emerging technological advances that will extend RNAi-based screening methods. |
| 巻・号 | 175(1) |
| ページ | 7-16 |
| 公開日 | 2007-1-1 |
| DOI | 10.1534/genetics.106.069963 |
| PII | 175/1/7 |
| PMID | 17244760 |
| PMC | PMC1775003 |
| MeSH | Animals Developmental Biology* Genome Humans Phenotype* RNA Interference* |
| IF | 4.015 |
| WOS 分野 | GENETICS & HEREDITY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 3 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 情報 | Drosophila |