RRC ID 19832
Author Ishida K, Murakami M.
Title Kasumigamide, an antialgal peptide from the cyanobacterium Microcystis aeruginosa.
Journal J Org Chem
Abstract Kasumigamide (1), a novel antialgal tetrapeptide containing an N-terminal alpha-hydroxy acid, was isolated from the freshwater cyanobacterium Microcystis aeruginosa (NIES-87). Its structure was elucidated by two-dimensional (1)H-(1)H and (1)H-(13)C NMR correlation experiments and confirmed by mass spectral and amino acid analyses. The absolute stereochemistry of 1 was determined by chemical studies. This peptide showed an antialgal activity against the green alga Chlamydomonas neglecta (NIES-439).
Volume 65(19)
Pages 5898-900
Published 2000-9-22
DOI 10.1021/jo991918f
PII jo991918f
PMID 10987919
MeSH Amino Acids / analysis Chlorophyta / drug effects* Chromatography, High Pressure Liquid Magnetic Resonance Spectroscopy Microcystis / chemistry* Oligopeptides / chemistry* Oligopeptides / isolation & purification Oligopeptides / toxicity Pesticides / chemical synthesis* Pesticides / pharmacology Spectrometry, Mass, Fast Atom Bombardment
IF 4.335
Times Cited 47
Algae NIES-439 NIES-87