RRC ID 20188
Author Watanabe F, Miyamoto E, Nakano Y.
Title Inactive corrinoid-compound significantly decreases in Spirulina platensis grown in a cobalt-deficient medium.
Journal J Agric Food Chem
Abstract Spirulina platensis NIES-39 was grown under open culture system in the presence or absence of CoSO(4) (12 microg/L) and/or vitamin B(12) (10 microg/L) to confirm whether CoSO(4) and/or vitamin B(12) stimulate or are essential for growth of the algal cells and for accumulation of vitamin B(12). The addition of CoSO(4) and/or vitamin B(12) could not affect both cell growth and cell yield of the alga. The amount of corrinoid-compound was increased significantly by the addition of CoSO(4) but not by vitamin B(12). A C18 reversed-phase HPLC pattern of the Spirulina corrinoid-compound increased by the addition of CoSO(4) was identical to that of authentic pseudovitamin B(12), which is inactive for human. These results indicate that the algal cells grown in the absence of CoSO(4) are suitable for use of human health foods because the inactive corrinoid-compound can be reduced significantly.
Volume 49(11)
Pages 5685-8
Published 2001-11-1
DOI 10.1021/jf010733i
PII jf010733i
PMID 11714378
MeSH Chromatography, High Pressure Liquid Cobalt / metabolism* Cobalt / pharmacology Corrinoids Culture Media Cyanobacteria / drug effects Cyanobacteria / growth & development Cyanobacteria / metabolism* Porphyrins / metabolism* Vitamin B 12 / metabolism Vitamin B 12 / pharmacology
IF 4.192
Times Cited 10
WOS Category AGRICULTURE, MULTIDISCIPLINARY CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY
Resource
Algae NIES-39