RRC ID 20374
Author Yoshida T, Maki M, Okamoto H, Hiroishi S.
Title Coordination of DNA replication and cell division in cyanobacteria Microcystis aeruginosa.
Journal FEMS Microbiol Lett
Abstract Little is known about the cyanobacterial cell cycle. When either nalidixic acid or hydroxyurea was added to a synchronized culture of Microcystis aeruginosa to block DNA replication, cell division did not occur. Furthermore, transcription of the essential cell division gene, ftsZ was repressed. After DNA replication, ftsZ transcription, as well as cell division, was not affected by hydroxyl urea, suggesting that the DNA replication and cell division of M. aeruginosa are coordinated and that this coordination is partly controlled by ftsZ transcription depending on DNA replication.
Volume 251(1)
Pages 149-54
Published 2005-10-1
DOI 10.1016/j.femsle.2005.07.041
PII S0378-1097(05)00530-6
PMID 16112821
MeSH Bacterial Proteins / physiology Cell Division* / drug effects Chromosomes, Bacterial / metabolism Colony Count, Microbial Cytoskeletal Proteins / physiology DNA Replication* / drug effects Hydroxyurea / pharmacology Microcystis / cytology Microcystis / physiology* Nalidixic Acid / pharmacology Nucleic Acid Synthesis Inhibitors / pharmacology Transcription, Genetic / drug effects
IF 1.987
Times Cited 23
WOS Category MICROBIOLOGY
Resource
Algae NIES-298