RRC ID 20776
Author Alamsjah MA, Ishibe K, Kim D, Yamaguchi K, Ishibashi F, Fujita Y, Oda T.
Title Selective toxic effects of polyunsaturated fatty acids derived from Ulva fasciata on red tide phyotoplankter species.
Journal Biosci Biotechnol Biochem
Abstract Alpha-linolenic acid and linoleic acid isolated from Ulva fasciata showed toxic effects on red tide phytoplankters in a concentration-dependent manner. Among six species tested, raphidophycean flagellate Heterosigma akashiwo was the most susceptible to these fatty acids, and 50% lethal concentrations (LC50) of alpha-linolenic acid and linoleic acid were estimated to be 0.58 and 1.91 microg/ml respectively, whereas dinoflagellate Gymnodinium impudicum and Heterocapsa circularisquama were highly resistant and no significant toxic effects were observed up to 1,000 microg/ml. Both fatty acids were less toxic to fish (devil stinger), zooplankters (brine shrimp and rotifer), and mammalian cell lines (U937, HeLa, Vero, and CHO cells) than H. akashiwo.
Volume 71(1)
Pages 265-8
Published 2007-1-1
DOI 10.1271/bbb.60475
PII JST.JSTAGE/bbb/60475
PMID 17213644
MeSH Animals Cell Line Cell Survival / drug effects Chlorocebus aethiops Cricetinae Dinoflagellida* Fatty Acids, Unsaturated / chemistry* Fatty Acids, Unsaturated / toxicity* Humans Phytoplankton / chemistry* Ulva / chemistry*
IF 1.516
Times Cited 9
WOS Category FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
Algae NIES-3