RRC ID 250
Author Naruse K, Tanaka M, Mita K, Shima A, Postlethwait J, Mitani H.
Title A medaka gene map: the trace of ancestral vertebrate proto-chromosomes revealed by comparative gene mapping.
Journal Genome Res.
Abstract The mapping of Hox clusters and many duplicated genes in zebrafish indicated an extra whole-genome duplication in ray-fined fish. However, to reconstruct the preduplication chromosomes (proto-chromosomes), the comparative genomic studies of more distantly related teleosts are essential. Medaka and zebrafish are ideal for this purpose, because their lineages separated from their last common ancestor approximately 140 million years ago. To reconstruct ancient vertebrate chromosomes, including the chromosomes of the vertebrate ancestor of humans from 450 million years ago, we mapped 818 genes and expressed sequence tags (ESTs) on a single meiotic backcross panel obtained from inbred strains of the medaka, Oryzias latipes. Comparisons of linkage relationships of orthologous genes among three species of vertebrates (medaka, zebrafish, and human) indicate the number and content of the chromosomes of the last common ancestor of ray-fined fish and lobe-fined fish (including humans), and the extra whole genome duplication event in the ray-fin lineage occurred in the common ancestor of perhaps all teleosts.
Volume 14(5)
Pages 820-8
Published 2004-5
DOI 10.1101/gr.2004004
PII 2004004
PMID 15078856
PMC PMC479108
MeSH Animals Chromosome Mapping / methods* Chromosomes / genetics* Chromosomes, Human / genetics Conserved Sequence / genetics Evolution, Molecular* Expressed Sequence Tags Gene Duplication Gene Expression Regulation / genetics Gene Silencing / physiology Genetic Linkage / genetics Genome Genome, Human Humans Multigene Family / genetics Oryzias / genetics* Ploidies Skates (Fish) / genetics Synteny / genetics Zebrafish / genetics
IF 9.944
Times Cited 195
WOS Category BIOTECHNOLOGY & APPLIED MICROBIOLOGY GENETICS & HEREDITY BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
Medaka HNI-II (IB176) AA2 (IB189)