RRC ID 2716
Author Sohda KY, Hiramoto M, Suzumura K, Takebayashi Y, Suzuki K, Tanaka A.
Title YM-216391, a novel cytotoxic cyclic peptide from Streptomyces nobilis. II. Physico-chemical properties and structure elucidation.
Journal J Antibiot (Tokyo)
Abstract YM-216391, a novel cytotoxic cyclic peptide, has been isolated from the cultured mycelium of Streptomyces nobilis JCM 4274. The planar structure of YM-216391 was assigned on the basis of 1D and 2D NMR spectroscopic techniques. The absolute configuration of the amino acid residues in YM-216391 was determined by Marfey's analysis and chiral HPLC analysis of its acid hydrolysate.
Volume 58(1)
Pages 32-6
Published 2005-1-1
DOI 10.1038/ja.2005.3
PMID 15813178
MeSH Antineoplastic Agents / analysis Antineoplastic Agents / chemistry* Antineoplastic Agents / isolation & purification Magnetic Resonance Spectroscopy Molecular Structure Oxazoles / analysis Oxazoles / chemistry Oxazoles / isolation & purification Peptides, Cyclic / analysis Peptides, Cyclic / chemistry Peptides, Cyclic / isolation & purification Streptomyces
IF 2.668
Times Cited 36
Resource
Pathogenic microorganisms JCM 4274?