Reference - Detail
| RRC ID | 27302 |
|---|---|
| Author | Erhard M, von Döhren H, Jungblut P. |
| Title | Rapid typing and elucidation of new secondary metabolites of intact cyanobacteria using MALDI-TOF mass spectrometry. |
| Journal | Nat Biotechnol |
| Abstract |
Toxic cyanobacterial blooms are a threat because of secondary metabolite production. We used matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to identify intact microorganisms. Microgram quantities of prepared cells, including solvent (acetonitrile and ethanol) and alpha-cyano-4-hydroxycinnamic acid matrix, display spectra showing predominantly the secondary metabolites including known microcystins, micropeptin, and anabaenopeptolin. A new cyclic anabaenopeptolin has been identified using the Post-Source-Decay mode. Strains of various origins can easily be typed according to their cyclic peptide production, and toxic and nontoxic algal blooms can be differentiated within minutes. |
| Volume | 15(9) |
| Pages | 906-9 |
| Published | 1997-9-1 |
| DOI | 10.1038/nbt0997-906 |
| PMID | 9306409 |
| MeSH | Anabaena / metabolism Bacterial Proteins / analysis* Cyanobacteria / metabolism* Microcystins Peptides, Cyclic / analysis* Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization |
| IF | 36.553 |
| Times Cited | 124 |
| WOS Category | BIOTECHNOLOGY & APPLIED MICROBIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Policy sources |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Algae | NIES-90 |