論文 - 詳細
| RRC ID | 27859 |
|---|---|
| 著者 | Suda T, Hata T, Kawai S, Okamura H, Nishida T. |
| タイトル | Treatment of tetracycline antibiotics by laccase in the presence of 1-hydroxybenzotriazole. |
| ジャーナル | Bioresour Technol |
| Abstract |
Tetracycline antibiotics are widely used in human and veterinary medicine; however, residual amounts of these antibiotics in the environment are of concern since they could contribute to selection of resistant bacteria. In this study, tetracycline (TC), chlortetracycline (CTC), doxycycline (DC) and oxytetracycline (OTC) were treated with laccase from the white rot fungus Trametes versicolor in the presence of the redox mediator 1-hydroxybenzotriazole (HBT). High performance liquid chromatography demonstrated that DC and CTC were completely eliminated after 15 min, while TC and CTC were eliminated after 1 h. This system also resulted in a complete loss of inhibition of growth of Escherichia coli and Bacillus subtilis and the green alga Pseudokirchneriella subcapitata with decreasing tetracycline antibiotic concentration. These results suggest that the laccase-HBT system is effective in eliminating tetracycline antibiotics and removing their ecotoxicity. |
| 巻・号 | 103(1) |
| ページ | 498-501 |
| 公開日 | 2012-1-1 |
| DOI | 10.1016/j.biortech.2011.10.041 |
| PII | S0960-8524(11)01507-0 |
| PMID | 22071243 |
| MeSH | Anti-Bacterial Agents / pharmacology* Bacillus subtilis / drug effects Bacillus subtilis / growth & development Bacillus subtilis / metabolism Chlorophyta / drug effects Chlorophyta / growth & development Escherichia coli / drug effects Escherichia coli / growth & development Escherichia coli / metabolism Humans Laccase / metabolism* Lignin / metabolism Tetracycline / pharmacology* Triazoles / pharmacology* |
| IF | 7.539 |
| 引用数 | 66 |
| WOS 分野 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY AGRICULTURAL ENGINEERING ENERGY & FUELS |
| リソース情報 | |
| 藻類 | NIES-35 |