論文 - 詳細
RRC ID | 29169 |
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著者 | Noguchi N, Katayama J, O'Hara K. |
タイトル | Cloning and nucleotide sequence of the mphB gene for macrolide 2'-phosphotransferase II in Escherichia coli. |
ジャーナル | FEMS Microbiol Lett |
Abstract |
Macrolide 2'-phosphotransferase II [MPH(2')II] inactivates macrolide antibiotics. The mphB gene for MPH(2')II was cloned from Escherichia coli and sequenced. Analysis of the nucleotide sequence indicated that mphB encoded a protein of 302 amino acids with a molecular mass of 34483 Da. The carboxy terminal region of the deduced protein contained a sequence that resembled a conserved functional domain in aminoglycoside phosphotransferases. |
巻・号 | 144(2-3) |
ページ | 197-202 |
公開日 | 1996-11-1 |
DOI | 10.1111/j.1574-6968.1996.tb08530.x |
PMID | 8900063 |
MeSH | Amino Acid Sequence Bacterial Proteins / genetics* Bacterial Proteins / metabolism Base Sequence Cloning, Molecular Escherichia coli / enzymology Escherichia coli / genetics* Escherichia coli Proteins Genes, Bacterial* Molecular Sequence Data Phosphotransferases (Alcohol Group Acceptor) / genetics* Phosphotransferases (Alcohol Group Acceptor) / metabolism Recombinant Fusion Proteins / metabolism Sequence Alignment Sequence Homology, Amino Acid |
IF | 1.987 |
引用数 | 34 |
WOS 分野 | MICROBIOLOGY |
リソース情報 | |
遺伝子材料 | mphB (pTZ37.16) (RDB01803) |