RRC ID 29169
著者 Noguchi N, Katayama J, O'Hara K.
タイトル Cloning and nucleotide sequence of the mphB gene for macrolide 2'-phosphotransferase II in Escherichia coli.
ジャーナル FEMS Microbiol Lett
Abstract Macrolide 2'-phosphotransferase II [MPH(2')II] inactivates macrolide antibiotics. The mphB gene for MPH(2')II was cloned from Escherichia coli and sequenced. Analysis of the nucleotide sequence indicated that mphB encoded a protein of 302 amino acids with a molecular mass of 34483 Da. The carboxy terminal region of the deduced protein contained a sequence that resembled a conserved functional domain in aminoglycoside phosphotransferases.
巻・号 144(2-3)
ページ 197-202
公開日 1996-11-1
DOI 10.1111/j.1574-6968.1996.tb08530.x
PMID 8900063
MeSH Amino Acid Sequence Bacterial Proteins / genetics* Bacterial Proteins / metabolism Base Sequence Cloning, Molecular Escherichia coli / enzymology Escherichia coli / genetics* Escherichia coli Proteins Genes, Bacterial* Molecular Sequence Data Phosphotransferases (Alcohol Group Acceptor) / genetics* Phosphotransferases (Alcohol Group Acceptor) / metabolism Recombinant Fusion Proteins / metabolism Sequence Alignment Sequence Homology, Amino Acid
IF 1.987
引用数 34
WOS 分野 MICROBIOLOGY
リソース情報
遺伝子材料 mphB (pTZ37.16) (RDB01803)