| RRC ID |
2928
|
| Author |
Girish Kumar CP, Hanafy AM, Katsu M, Mikami Y, Menon T.
|
| Title |
Molecular analysis and susceptibility profiling of Candida albicans isolates from immunocompromised patients in South India.
|
| Journal |
Mycopathologia
|
| Abstract |
The genetic diversity and in vitro antifungal susceptibility profiles of 55 Candida albicans from immunocompromised patients were studied. PCR based analysis of the transposable intron in the 25S rDNA revealed 39 genotype A, 4 genotype B and 12 genotype C isolates. Serotype analysis categorized 52 isolates as serotype A and 3 as serotype B. All strains were susceptible to micafungin, 5-flucytosine and miconazole, whereas resistance against amphotericin B (3.6%), fluconazole (3.6%), itraconazole (7.3%) and voriconazole (5.5%) was observed. No association was seen between antifungal resistance and genotype/serotype status.
|
| Volume |
161(3)
|
| Pages |
153-9
|
| Published |
2006-3-1
|
| DOI |
10.1007/s11046-005-9210-6
|
| PMID |
16482387
|
| MeSH |
Antifungal Agents / pharmacology*
Candida albicans / drug effects*
Candida albicans / genetics*
Candida albicans / isolation & purification
Candidiasis / immunology*
Candidiasis / microbiology*
DNA, Fungal / chemistry
DNA, Fungal / genetics
Genetic Variation
Genotype
Humans
Immunocompromised Host*
India
Microbial Sensitivity Tests
Polymerase Chain Reaction
RNA, Ribosomal / chemistry
RNA, Ribosomal / genetics
Serotyping
|
| IF |
2.452
|
| Times Cited |
10
|
| Resource |
| Pathogenic microorganisms |
IFM 40213
IFM 40214
IFM 48313
IFM 52112 |
