Reference - Detail
| RRC ID | 2934 |
|---|---|
| Author | Hirayama T, Tamegai H, Kudo F, Kojima K, Kakinuma K, Eguchi T. |
| Title | Biosynthesis of 2-deoxystreptamine-containing antibiotics in Streptoalloteichus hindustanus JCM 3268: characterization of 2-deoxy-scyllo-inosose synthase. |
| Journal | J Antibiot (Tokyo) |
| Abstract |
A part of the new biosynthetic gene cluster for 2-deoxystreptamine-containing antibiotics was identified from Streptoalloteichus hindustanus. The alloH gene in the gene cluster was deduced to encode 2-deoxy-scyllo-inosose synthase and the expressed protein AlloH was confirmed to have this enzyme activity. Furthermore, biochemical properties of AlloH were studied. |
| Volume | 59(6) |
| Pages | 358-61 |
| Published | 2006-6-1 |
| DOI | 10.1038/ja.2006.51 |
| PMID | 16915821 |
| MeSH | Actinomycetales / genetics Actinomycetales / metabolism* Anti-Bacterial Agents / biosynthesis* Hexosamines / biosynthesis Lyases / genetics* Multigene Family |
| IF | 2.668 |
| Times Cited | 10 |
| WOS Category | BIOTECHNOLOGY & APPLIED MICROBIOLOGY PHARMACOLOGY & PHARMACY IMMUNOLOGY MICROBIOLOGY |
| Resource | |
| Pathogenic microorganisms | JCM 3268 |