Reference - Detail
| RRC ID | 29474 |
|---|---|
| Author | Yamauchi N, Nakayama Y. |
| Title | Biosynthetic mechanism for L-Gulose in main polar lipids of Thermoplasma acidophilum and possible resemblance to plant ascorbic acid biosynthesis. |
| Journal | Biosci Biotechnol Biochem |
| Abstract |
L-Gulose is a very rare sugar, but appears as a sugar component of the main polar lipids characteristic in such a thermophilic archaeon as Thermoplasma acidophilum that lives without cell walls in a highly acidic environment. The biosynthesis of L-gulose in this thermophilic organism was investigated with deuterium-labeling experiments. L-Gulose was found to be biosynthesized from D-glucose via stepwise stereochemical inversion at C-2 and C-5. The involvement of an epimerase related to GDP-mannose 3,5-epimerase, the key enzyme of plant ascorbate biosynthesis, was also suggested in this C-5 inversion. The resemblance of L-gulose biosynthesis in archaea and plants might be suggested from these results. |
| Volume | 77(10) |
| Pages | 2087-93 |
| Published | 2013-1-1 |
| DOI | 10.1271/bbb.130442 |
| PII | DN/JST.JSTAGE/bbb/130442 |
| PMID | 24096672 |
| MeSH | Ascorbic Acid / biosynthesis* Glucose / metabolism Hexoses / biosynthesis* Hexoses / chemistry Lipids / chemistry* Plants / metabolism* Stereoisomerism Thermoplasma |
| IF | 1.516 |
| Times Cited | 0 |
| WOS Category | BIOCHEMISTRY & MOLECULAR BIOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY |
| Resource | |
| General Microbes | JCM 9062 |