論文 - 詳細
| RRC ID | 3052 |
|---|---|
| 著者 | Vidotto V, Ito-Kuwa S, Nakamura K, Aoki S, Melhem M, Fukushima K, Bollo E. |
| タイトル | Extracellular enzymatic activities in Cryptococcus neoformans strains isolated from AIDS patients in different countries. |
| ジャーナル | Rev Iberoam Micol |
| Abstract |
Three hundred and ten Cryptococcus neoformans strains isolated from AIDS patients in five different countries (151 from Brazil, 23 from Italy, 28 from Spain, 104 from Thailand and four from Turkey) were tested by the API-ZYM kit to detect their extracellular enzymatic activity. The enzymes esterase (C4) (no 3), esterase lipase (C8) (no 4), leucine arylamidase (no 6) and acid phosphatase (no 11) were commonly positive in most of the strains (more than 95%). These enzymes could be considered a useful tool not only for C. neoformans identification, but in particular for their possible relationship to new C. neoformans virulence factors and also for epidemiological research. Interestingly, it is also the high positive percentage of alpha-glucosidase and beta-glucosidase detected in all isolates. The serotype A was the most predominant serotype in all countries, except for Italy where the serotype D was predominant. Further studies are needed to draw a clear correlation between the API-ZYM profile and serotype. |
| 巻・号 | 23(4) |
| ページ | 216-20 |
| 公開日 | 2006-12-1 |
| DOI | 10.1016/s1130-1406(06)70047-x |
| PII | 200623216 |
| PMID | 17388645 |
| MeSH | AIDS-Related Opportunistic Infections / enzymology* AIDS-Related Opportunistic Infections / epidemiology AIDS-Related Opportunistic Infections / microbiology Bacterial Typing Techniques / methods* Brazil / epidemiology Clinical Enzyme Tests Cryptococcosis / diagnosis Cryptococcosis / enzymology* Cryptococcosis / epidemiology Cryptococcosis / microbiology Cryptococcus neoformans / classification Cryptococcus neoformans / enzymology* Cryptococcus neoformans / isolation & purification Cryptococcus neoformans / pathogenicity Extracellular Fluid / enzymology Fungal Proteins / isolation & purification* Humans Italy / epidemiology Serotyping Spain / epidemiology Thailand / epidemiology Turkey / epidemiology Virulence |
| IF | 1.627 |
| リソース情報 | |
| 病原微生物 | |