Reference - Detail
| RRC ID | 30691 |
|---|---|
| Author | Tanaka KM, Takahashi A, Fuse N, Takano-Shimizu-Kouno T. |
| Title | A novel cell death gene acts to repair patterning defects in Drosophila melanogaster. |
| Journal | Genetics |
| Abstract |
Cell death is a mechanism utilized by organisms to eliminate excess cells during development. Here, we describe a novel regulator of caspase-independent cell death, Mabiki (Mabi), that is involved in the repair of the head patterning defects caused by extra copies of bicoid in Drosophila melanogaster. Mabiki functions together with caspase-dependent cell death mechanisms to provide robustness during development. |
| Volume | 197(2) |
| Pages | 739-42 |
| Published | 2014-6-1 |
| DOI | 10.1534/genetics.114.163337 |
| PII | genetics.114.163337 |
| PMID | 24671768 |
| PMC | PMC4063928 |
| MeSH | Animals Body Patterning / genetics* Cell Death / genetics Drosophila Proteins / genetics Drosophila Proteins / metabolism* Drosophila melanogaster / embryology* Drosophila melanogaster / genetics Gene Expression Regulation, Developmental* Gene Knockdown Techniques Head / embryology |
| IF | 4.015 |
| Times Cited | 1 |
| WOS Category | GENETICS & HEREDITY |
| Resource | |
| Drosophila | DrosDel deficiencies |